Axolotls Can Regenerate Their Own Brains: New research maps out the different cell types hoping to pave the way to regenerative medicine!
O.o!!!
According to recent research, the protein CHIP can control the insulin receptor more effectively while acting alone than when in a paired state. In cellular stress situations, CHIP often appears as a homodimer – an association of two identical proteins – and mainly functions to destroy misfolded and defective proteins. CHIP thus cleanses the cell. In order to do this, CHIP works with helper proteins to bind a chain of the small protein ubiquitin to misfolded proteins.
As a result, the cell detects and gets rid of defective proteins. Furthermore, CHIP controls insulin receptor signal transduction. CHIP binds to the receptor and degrades it, preventing the activation of life-extending gene products.
Continue reading “Scientists Discover a Molecular Switch That Controls Life Expectancy” »
Are you looking for the most recent Artificial Intelligence Trends? Artificial intelligence will have advanced far enough to become the most revolutionary technology ever devised by man. Artificial intelligence (AI) is progressing at an alarming rate. At the moment, new technical applications and systems are being employed to imitate, extend, and expand human intelligence.
Curious to know more? stay connected for that as we dive deeper!
Continue reading “BREAKTHROUGH! The Gap between the Human Brain and Ai is closed!” »
Article originally published on LINKtoLEADERS under the Portuguese title “Sem saber ler nem escrever!”
In the 80s, “with no knowledge, only intuition”, I discovered the world of computing. I believed computers could do everything, as if it were an electronic God. But when I asked the TIMEX Sinclair 1000 to draw the planet Saturn — I am fascinated by this planet, maybe because it has rings —, I only glimpse a strange message on the black and white TV:
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SINGAPORE — A new longevity clinic where the doctor will diagnose a healthy person’s biological age and then provide a customised plan to slow ageing is being set up at Alexandra Hospital and is expected to open by early next year.
It will be the first publicly funded outpatient clinic in longevity medicine in Singapore and possibly in the world, Professor Andrea Maier, the co-director of the National University Health System (NUHS) Centre for Healthy Longevity told The Straits Times at the sidelines of the centre’s opening on Wednesday.
The clinic will be manned by internal medicine specialists like Prof Maier, who is also the founding president of the International Longevity Medicine Society that was set up last month.
Water is a key ingredient to all life on Earth, yet tardigrades with their near immortal-like powers can somehow endure being sapped of almost all their H2O.
Now, researchers have discovered another trick these chubby microscopic anomalies use to survive years of extreme dehydration.
“Although water is essential to all life we know of, some tardigrades can live without it potentially for decades,” says University of Tokyo biologist Takekazu Kunieda.
Excerpt from an interview by Rich Roll to Peter Diamandis, founder and executive officer of XPrize Foundation, co-founder of Singularity University in Silicon Valley, CA., three-time best selling author, public speaker, philanthropist, and prolific investor.
Peter Diamandis has started over 20 companies in the areas of longevity, space, venture capital and education.
Ageing, defined as the decline in survival probability and fecundity with advancing adult age, is often viewed as the evolutionary outcome of the declining force of natural selection at older age (17 ; 22). Ageing can be due to the accumulation of late acting deleterious mutations (17 ; 12 ; 4), and/or due to pleiotropy, as the result of constrained life-history optimization (36 ; 4 ; 22 ; 38). For instance, increased allocation of limited resources to reproduction can be an important cause of senescence and later mortality (17 ; 35 ; 14 ; 15 ; 31). Most of the evidence for this phenomenon comes from experiments showing the deleterious consequences of an increase in reproductive effort on life span (21 ; 32 ; 3 ; 10 ; 24 ; 28). Artificial selection on age at reproduction showed the reverse effect that selection regime favouring individuals that retained fecundity at a later age resulted in populations with increased life spans (7 ; 39 ; 22). Data for higher organisms, e.g. mammals, have until now been mostly lacking.
The hypothesis that investment in reproduction reduces the resources available for somatic maintenance has recently been tested in Homo sapiens by 33 ). Using 1,200 years of genealogical data on British aristocracy, they showed that the number of progeny was small for women who died at an early age, increased with the age of death, reached a plateau through the sixth, seventh and eighth decades of life, and was lower again for women who died at an age of 80 years or over. This relationship supported the expectation that heavy investments in reproduction diverts resources away from the maintenance and repair of cells, with ageing and earlier death as results (33). For unknown reasons, the authors found a virtually identical pattern among men.
As manipulative experiments on humans are unethical, the statistical search for congruent patterns offers an alternative to understand variation in life-history parameters among human populations. Fortunately, there are considerable statistics on humans and their activities, and other ways of detecting similar patterns and of testing relevant hypotheses are possible. The aim of the present paper is to assess the generality of this trade-off among humans. We test whether the variation of life-history parameters found in the study of British aristocrats is also present across different human populations worldwide. After controlling longevity and fecundity for possible effects exerted by historical, spatial, economical and population patterns, we determined the relationship between longevity and fecundity, using data from 153 countries located all over the world.
One of the most upsetting aspects of age-related memory decline is not being able to remember the face that accompanies the name of a person you just talked with hours earlier. While researchers don’t understand why this dysfunction occurs, a new study conducted at University of Maryland School of Medicine (UMSOM) has provided some important new clues. The study was published on September 8 in Aging Cell.
Using aging mice, researchers have identified a new mechanism in neurons that causes memories associated with these social interactions to decline with age. In addition, they were able to reverse this memory loss in the lab.
The researchers report that their findings identified a specific target in the brain that may one day be used to develop therapies that could prevent or reverse memory loss due to typical aging. Aging memory problems are distinct from those caused by diseases like Alzheimer’s or dementia. At this time, there are no medications that can prevent or reverse cognitive decline due to typical aging.
