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Category: life extension

New roles found for STIP1 and Maspin proteins in cell renewal and structure

Two recently published studies led by Brazilian scientists reveal the key roles of multifunctional proteins, STIP1 and Maspin, in vital cellular processes.

The results demonstrate new functions that help clarify how cells maintain their shape, communicate, and renew themselves. These findings contribute to new studies on cancer, embryogenesis, and potential applications in .

According to one of the studies, STIP1 plays a central role in and maintaining pluripotency, or the ability of cells to multiply and give rise to other .

Our BRLS Research Application, Fixation vs. Vitrification Reflection, Cryonics & Autism

In this epsiode of the Cryosphere chat we discuss:
● The research proposal we submitted to BRLS
● Why slow growth could be an existential risk to cryonics.
● Our review of the Fixation vs. Vitrification discussion.
● Why there are so many autistic cryonicists.

Links:
Fixation vs. Virtification Discussion: https://youtu.be/gvu8P9D6p0g?si=2KOSESeOndtVl33V
Biostasis Pacific Northwest: https://www.reddit.com/r/cryonics/comments/1ozxslv/announcin…northwest/
I’ll see ya later mom… Reddit post: https://www.reddit.com/r/cryonics/comments/1owgnk0/ill_see_ya_later_mom/
Cryosphere Discord: https://discord.gg/ndshSfQwqz

This 250-Year-Old Whale Might Hold the Key to Human Longevity

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/
Timestamps:
00:00 Intro.
00:41 DNA damage and aging.
01:37 Why bowhead whales live so long.
03:13 Cold shock proteins and lifespan.
04:43 Body temperature and longevity.
06:50 Acute cold exposure benefits.
08:10 Takeaway.

100 Health Biomarkers Ranked: https://youtu.be/SgKp5mm0ALI?si=M7YkYo6Lelci7kOQ

Start rewinding your biological clock: https://www.siimland.co/course.

P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Single-celled organisms have more complex DNA epigenetic code than multicellular life, researchers discover

Multicellular organisms (animals, plants, humans) all have the ability to methylate the cytosine base in their DNA. This process, a type of epigenetic modification, plays an important role in conditions such as cancer and processes such as aging.

In a paper appearing in Nature Genetics, researchers discover that in more “primitive” unicellular organisms, both the adenine and the cytosine bases are methylated. This would suggest that in some ways, these unicellular organisms are more complex than their multicellular peers.

The team also found that methylation of the adenine base was, in the case of many of these unicellular organisms, vital for controlling which genes are switched on, which is important for their viability.

A Common Diabetes Drug Is Linked to ‘Exceptional Longevity’ in Women

Not only can the drug metformin help to effectively manage type 2 diabetes, but it may also give older women a better chance of living to the grand old age of 90, according to recent research – thanks, it seems, to a variety of anti-aging effects.

Scientists in the US and Germany used data from a long-term US study of postmenopausal women. Records on a total of 438 people were picked out – half of whom took metformin to treat diabetes, and half who took a different diabetes drug, called sulfonylurea.

While there are some caveats and asterisks to the study, those in the metformin group were calculated to have a 30 percent lower risk of dying before the age of 90 than those in the sulfonylurea group.

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