The maternal-fetal interface is a specialized immunological barrier that integrates tolerance, defense, and regulated inflammation throughout gestation. Distinct immune populations mediate implantation, immune homeostasis, and parturition, while dysregulation can result in chronic placental inflammation, a consequence of barrier failure, characterized by infiltration of maternal T cells into placental/fetal tissues.
Open source engine PlayCanvas is what Iakov Sumygin used to build that browser-based FPS. Resources like this strengthen Schindelar’s case, particularly as the engine just introduced SplatTransform 2.0, a tool that offers “fully automated, lightning-fast generation of high-quality collision for your splats.” Without a collision mesh, players could otherwise phase through the environment, so this is yet another option that streamlines the pipeline between scan and interactive assets.
“Gaussian Splatting training—meaning the reconstruction process after capture—can reproduce real-world appearance in ways that traditional scanning methods struggle with or cannot handle properly,” He tells me, “We can now capture and represent things like hair, semi-transparency, translucency, subsurface scattering, fine foliage, and other complex visual phenomena that are extremely difficult to reconstruct as clean geometry with traditional texture workflows.”
“This direct connection between captured real-world data and a production-ready, real-time representation is what makes Gaussian Splatting so interesting,” Schindelar says, “It is not just a rendering trick—it changes the entire capture-to-delivery pipeline.”
Late last month, Jurassic Park actor Sam Neill put the treatment in the spotlight, revealing his stage three cancer was in remission after undergoing CAR T-cell therapy as part of a clinical trial in Sydney. He stopped short of describing his remission as a miracle – the success, he said, was “science at its best”
The history of CAR (for “chimeric antigen receptor”) T-cell therapy is one of small discoveries accumulating over decades, leading to major advances in patient care. Pioneered in the 1990s, the therapy has exploded in the past decade. Four CAR T-cell therapies have been approved by the Therapeutic Goods Administration for use in Australia since 2018. All are for blood cancers.
The success of those therapies is increasing enthusiasm among researchers and clinicians that CAR T-cell therapies will soon become a major weapon in the battle against cancer. It is now being tweaked to combat solid tumours, with promising early signs of success tempered by the difficulties in tailoring T-cells to find their target. The future may even see it become an injectable.
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