WhatsApp is rolling out username reservations globally, letting users reserve unique names before the privacy feature launches later this year.
I show how the time dilation derived in special relativity by assuming an abstract concept of malleable time, can be derived in a more mechanistic manner by assuming that the cosmos is like a simulation \& time is a processing delay.
I had this idea while playing minecraft with my son — every time I approached a large villager-town the PC slowed down and I thought \.
Self-amplifying RNA is synthetic nucleic acid engineered to replicate within cells without generating viral particles. Derived from alphavirus genomes, saRNA retains the non-structural elements essential for replication while replacing the structural elements with an antigen of interest. By enabling efficient intracellular amplification, saRNA offers a promising alternative to conventional mRNA vaccines, enhancing antigen expression while requiring lower doses. However, this advantage comes with challenges. In this review, we highlight the key limitations of saRNA technology and explore potential strategies to overcome them. By identifying these challenges, we aim to provide insights that can guide the future design of saRNA-based therapeutics, extending their potential beyond vaccine applications.
Self-amplifying RNA is synthetic nucleic acid engineered to replicate within cells without generating viral particles. Derived from alphavirus genomes, saRNA retains the non-structural elements essential for replication while replacing the structural elements with an antigen of interest. By enabling efficient intracellular amplification, saRNA offers a promising alternative to conventional mRNA vaccines, enhancing antigen expression while requiring lower doses. However, this advantage comes with challenges. In this review, we highlight the key limitations of saRNA technology and explore potential strategies to overcome them. By identifying these challenges, we aim to provide insights that can guide the future design of saRNA-based therapeutics, extending their potential beyond vaccine applications.
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Timestamps:
00:00 — New Semiconductor.
08:44 — Computers of The Future.
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Unlike some other spiders that camouflage themselves with drab colors and sticklike appendages, the jumping spider Siler collingwoodi disguises itself by the way it moves. The bright blue and orange arachnid—a pea-size animal native to China and Japan—crawls like an ant, according to a new study.
In a side-by-side comparison, researchers found that S. collingwoodi spiders copied the movements of multiple spikey, aggressive species of ants. The spiders walked at a similar pace, bobbed their abdomens like the ants did, and elevated their first pair of legs when they walked, imitating antennae.
(Cell Reports 45, 117350; May 26, 2026)
In the originally published version of this article, there was an error with Figure 3H that occurred during the final preparation of the manuscript, where some of the cellular images were displayed as black panels. The figure has been replaced with a corrected Figure 3H where the cellular images are now visible.
The authors regret this error.