Our researchers are combining steroids and a specially formulated diet to make a new type of glioblastoma treatment.
Claude Code flaws allow remote code execution and API key theft via untrusted repositories; three bugs fixed across 2025–2026 releases.
Online now: This study shows that a key metabolic enzyme, PCK1, protects the liver from scarring by keeping fibrogenic cells in a quiescent state. When PCK1 is reduced, these cells undergo metabolic reprogramming characterized by increased glycolysis, become aberrantly activated, and promote liver fibrosis in mice.
New in JBC press| Scientists examine the effects of conditional knockouts of alpha2 spectrin in postnatal outer hair cells.
asbmbJBC.
Electromotility in mammalian outer hair cells (OHC) is the mechanism underlying cochlear amplification. It is brought about by the piezoelectric-like property of the membrane protein prestin (Slc26a5) that lies in the OHCs lateral plasma membrane. Prestin connects to an underlying cytoskeletal network of circumferential actin filaments that bridge longitudinal spectrin filaments. This network, in turn, lies between the plasma membrane and a closely apposed ER-like tubular array of subsurface cisternae (SSC).