Scientists have found a way to trap light in an extremely thin layer, potentially reshaping how future photonic devices are built.
Glutathione is critical for NK cell-mediated immunity.
Guerra et al. show that glutathione (GSH) sustains IL-15-driven NK cell metabolism and effector functions. Loss of GSH unleashes T cell immunity and improves viral clearance. In contrast, NK cell-mediated control of metastases, but not solid tumors, critically depends on GSH.
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Study findings reveal noteworthy changes in immune cell activation and exhaustion markers that may contribute to immune vulnerability after spinal cord injury, offering novel insights into potential therapeutic targets, such as NAD+ metabolism and immune checkpoint modulation.
Background and Objectives.
What is the farthest place ever reached in Star Trek?From dangerous nebulae just a few hundred light-years away… to the literal edge of the observable univer…