To harness biological systems (plants and microbes) for next-generation energy production and advanced materials, researchers are looking to beneficial plant-microbe interactions. Because these are complex systems, it has proven difficult to reproducibly control exactly which microbes are present. And, subtle differences in materials, methods, or even the hands of the researchers themselves can lead to inconsistent results. This makes it difficult to replicate previous work, significantly slowing the leap from scientific discovery to practical application.
Researchers at Lawrence Berkeley National Laboratory (Berkeley Lab) are overcoming this bottleneck by addressing a multi-layered challenge: building reliable physical hardware, engineering accurate visual sensors, and developing predictive algorithms. Their solution, EcoBOT, stands out from typical plant phenotyping facilities by integrating these distinct components into a reliably automated workflow under strictly sterile conditions.
EcoBOT takes specialized growth chambers, called EcoFABs, and integrates them with machine-learning tools that autonomously guide the discovery cycle. This system uses advanced imaging to regularly scan the entire plant—from the tips of its leaves to the bottom of its roots. By using Gaussian Process models and AI analysis tools, it can quickly analyze and model this visual data to calculate the most informative next steps. This directs the automated hardware to determine exactly how plants adapt to environmental stressors, establishing the crucial microbe-free baseline needed to eventually study plant-microbe interactions and engineer better bioenergy crops.
