Wireless communication is about to get stronger, clearer, and more secure, thanks to a new idea from UBC Okanagan researchers. Dr. Anas Chaaban and his team in the School of Engineering are exploring a method to improve the way stacked intelligent surfaces (SIS) can process electromagnetic waves more efficiently.
SIS is an emerging alternative to conventional wireless hardware, Dr. Chaaban says, as layers of specially engineered materials are used to directly manipulate electromagnetic waves.
“Electromagnetic waves travel through special surfaces that consist of several elements. These elements mimic neurons in a computerized neural network,” Dr. Chaaban says. “As the waves move through the surface, each element changes them slightly. When the waves come out, they are captured by antennas that send the signals to digital processors for further analysis.”
Microglial lysosomes immune activation and protein turnover.
In addition to its role in protein and organelle homeostasis, lysosomes are also involved in nutrient sensing, cell metabolism, immune response, and programmed cell death.
Lysosomes are heterogeneous subpopulations and their dysfunction has been associated with the pathogenesis of several neurodegenerative diseases.
Although lysosomal biogenesis, transport, and heterogeneity are well studied in neurons, the researchers in this review discuss microglial lysosome biology its regulation, composition, and function, and how these properties are linked to immune activation, aging, and certain disease pathologies. sciencenewshighlights Science Mission https://sciencemission.com/microglial-lysosomes
Npj Dementia — “Micro-managing” immune activation and protein turnover: microglial lysosomes in the context of health and disease. npj Dement. 2, 35 (2026). https://doi.org/10.1038/s44400-026-00086-8
Neuroblastoma is an unusual tumor disease of the nervous system that almost exclusively affects children, mainly younger than two years old. About half of the children have high-risk tumors with a lower chance of being cured. N-MYC is linked to poorer prognosis in neuroblastoma.
Most proteins have a definite three-dimensional structure that usually contributes to their function and how they interact with other proteins. MYC is different and does not really have a fixed three-dimensional structure. The protein is flexible and constantly changes shape, which poses a challenge to researchers seeking to understand how MYC proteins work.
Also, MYC proteins are involved in the processes necessary for healthy cells to grow and divide. To prevent all cells in the body being harmed, it is important that a drug inhibits only the MYC function that is the problem in cancer cells, and nothing else. In other words, it takes a molecule that specifically affects a certain interaction between N-MYC and another protein.
In the current study, the researchers focused on the protein Aurora A, which also has a role in neuroblastoma and many other tumor forms. Preventing these proteins from interacting with each other has been suggested as a way to treat childhood tumors.
“To stop an interaction, you need to know where it’s happening. Despite the fact that N-MYC constantly changes shape, we now know where the two proteins anchor to each other. This provided clues as to what the medication should look like. We’ve also found a small molecule that manages to break apart the proteins, which lays a good foundation for future clinical trials,” says the first author.
The authors show that N-Myc binding to the Aurora A N-lobe can be inhibited by the small-molecule AurkinA, providing opportunity for therapeutical strategies to disrupt this interaction. ScienceMission sciencenewshighlights.
The Delayed Choice Quantum Eraser explained simply provides a shocking answer to whether the future affects the past. Could it be possible that that the future can influence the present? An enhanced version of the famous double slit experiment, called the delayed choice quantum eraser implies exactly that mind blowing scenario – that future events can influence past results.
What exactly is a delayed choice quantum eraser, and how can it possibly show that the future is affecting the past? In 1978, a physicist by the name of John Archibald Wheeler proposed a thought experiment, called delayed choice. Wheeler’s idea was to imagine light from a distant quasar being gravitationally lensed by a closer galaxy. Wheeler noted that this light could be observed on earth in two different ways. This is called a delayed choice because the observer’s choice of selecting how to measure the particle is being done billions of years from the time that the particle left the quasar.
But how could this be?…the light began its journey billions of years ago, long before we decided on which experiment to perform. It would seem as if the quasar light “knew” whether it would be seen as a particle or wave billions of years before the experiment was even devised on earth. Does this prove that somehow the particle’s measurement of its current state has influenced its state in the past? The act of measurement gives reality to the quantum particle. So in the delayed-choice experiment, this means the quantum doesn’t become “real” until you measure it. So this experiment does not prove that the present has influenced the past because the light could have been a wave and particle at the same time, and only become real when it was measured.
However, another more recent experiment set up used a more complicated method to determine this idea of the future influencing a past. It introduced something called the quantum eraser to the delayed choice. So it is called the Delayed Choice Quantum Eraser designed by Kim, Kulik, Shih and Scully in 1999.
It is a complicated construction that introduced entangled pairs of photons to Wheeler’s delayed choice experiment.
I am going to show you a much simpler set up that will illustrate this concept in easier-to-understand terms. The results of this experiment are pretty amazing — because Here’s what happens. It tells us that when the which way information is known, that is, when the detector can ascertain which slit the photon came from, it always presents as a particle. But when the detector cannot ascertain which slit the photon came from, that is, when the which way information is erased, then the photon acts like a wave.
Alain Aspect, John Clauser and Anton Zeilinger conducted ground breaking experiments using entangled quantum states, where two particles behave like a single unit even when they are separated. Their results have cleared the way for new technology based upon quantum information.
0:00 The 2022 Physics Nobel Prize 0:51 Is the Universe Real? 1:58 Einstein’s Problem with Quantum Mechanics 5:09 The Hunt for Quantum Proof 7:37 The First Successful Experiment 11:06 So What?
#Einstein #nobelprize #entanglement.
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Quantum mechanics has a lot of weird stuff — but there’s thing that everyone agrees that no one understands. I’m talking about quantum spin. Let’s find out how chasing this elusive little behavior of the electron led us to some of the deepest insights into the nature of the quantum world.
Now, as artificial intelligence enters the classroom, proponents argue it will be a welcome revolution for schools — but with limited guardrails, could it do more harm than good? Horizons moderator William Brangham explores the future of AI and education with Khan Academy founder Salman Khan, who has launched a new AI assistant for teachers.
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Our most massive satellite galaxy, the Large Magellanic Cloud (LMC), has been the center of a heated debate in the astrophysics community over the last few years. That debate centers on whether this is the LMC’s first or second “pass” by the Milky Way itself — and it has huge implications for the evolution of our galaxy given the disruption such a large grouping of stars has. A new paper from Scott Lucchini, Jiwon Jesse Han, Sapna Mishra, and Andrew J. Fox and his co-authors, currently available in pre-print on arXiv, provides what they claim to be definitive evidence that this is, in fact, the first time LMC has encountered the Milky Way.
To understand the debate, it’s best to look at its history. For decades, there was an ongoing debate about the orbital path of the LMC. The discussion centered around a collisionless N-body dynamics model that tracked stars and their gravity. But back in 2024, physicist Eugene Vasiliev released a stunning paper that presented an argument that the LMC might have first passed the Milky Way 6–8 billion years ago at a distance of roughly 100 kiloparsecs.
Upon release of that paper, the debate was reignited. Vasiliev posited that, if the Milky Way’s dark energy halo was anisotropic (meaning the velocities of dark matter particles are skewed in certain directions), the current speed and position of the LMC would align perfectly with a “second pass” orbit. Dr. Lucchini and his co-authors are firmly on the other side of that argument.
Russia is developing what officials have described as a “vaccine against aging,” a gene therapy drug aimed at slowing cellular aging by blocking a receptor linked to age-related changes in the body, the deputy science minister said Thursday.
Denis Sekirinsky, Russia’s deputy science and higher education minister, said the experimental treatment would target the RAGE receptor, which he said triggers cellular aging when activated.
“The RAGE gene is a receptor whose activation launches the aging of the cell. Blocking this gene, on the contrary, can prolong its youth,” Sekirinsky said at a healthy longevity conference in the Volga city of Saransk, according to the state-run TASS news agency.
