Ji, J., Ye, Z., Wang, Z. et al. Light Sci Appl 14, 332 (2025). https://doi.org/10.1038/s41377-025-02014-6
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Is Chronic Kidney Disease Due to Cadmium Exposure Inevitable and Can It Be Reversed?
Cadmium (Cd) is a metal with no nutritional value or physiological role. However, it is found in the body of most people because it is a contaminant of nearly all food types and is readily absorbed. The body burden of Cd is determined principally by its intestinal absorption rate as there is no mechanism for its elimination. Most acquired Cd accumulates within the kidney tubular cells, where its levels increase through to the age of 50 years but decline thereafter due to its release into the urine as the injured tubular cells die. This is associated with progressive kidney disease, which is signified by a sustained decline in the estimated glomerular filtration rate (eGFR) and albuminuria. Generally, reductions in eGFR after Cd exposure are irreversible, and are likely to decline further towards kidney failure if exposure persists.
“Substrate-dependent mathematics hypothesis” by Olaf Witkowski
This is a ~50-minute talk titled “Substrate-dependent mathematics hypothesis” by Olaf Witkowski (https://olafwitkowski.com/), presented for our Platonic Space symposium (https://thoughtforms.life/symposium-on-the-platonic-space/).
Intel & NVIDIA Announce Strategic Collaboration
This collaboration will integrate NVIDIA’s AI and accelerated computing technologies with Intel’s CPUs and x86 ecosystem, using NVIDIA NVLink for seamless connectivity.
For data centers, Intel will build NVIDIA-custom x86 CPUs that NVIDIA will integrate into its AI infrastructure platforms and offer to the market. However, the spotlight is on personal computing, for which Intel will build and offer to the market x86 system-on-chips (SOCs) that integrate NVIDIA RTX GPU chiplets. These new x86 RTX SoCs are designed to “power a wide range of PCs that demand integration of world-class CPUs and GPUs.”
Are tech monopolies just becoming even bigger monopolies with less competition? It’s worth noting that Intel has actually done something similar before with AMD, and Kaby Lake-G is now largely viewed as a failure. Still, it’s hard to imagine this happening if Intel weren’t facing serious challenges. NVIDIA’s $5 billion investment in Intel, through common stock purchased at $23.28 per share, goes beyond a mere hint.
Rice researchers create novel metamaterial that can potentially revolutionize implantable, ingestible devices
Researchers led by Rice’s Yong Lin Kong have developed a soft but strong metamaterial that can be controlled remotely to rapidly transform its size and shape.