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Scientists catch antimatter “atom” acting like a wave for the first time

Quantum physics once shocked scientists by revealing that particles can behave like waves—and now, that strange behavior has been pushed even further. For the first time, researchers have observed wave-like interference in positronium, an exotic “atom” made of an electron and its antimatter partner, a positron. This breakthrough not only strengthens the weird reality of quantum mechanics but also opens the door to new experiments involving antimatter, including the possibility of testing how gravity affects it—something never directly measured before.

AI could help human scientists pick promising research topics

Large language models (LLMs) could help human scientists identify interesting research topics that have not previously been explored, say scientists at Germany’s Karlsruhe Institute of Technology (KIT). By analysing abstracts in materials science publications and mapping connections between different concepts, the model was able to generate predictions for future areas of interest that the KIT team says are more precise than those produced by traditional, rule-based algorithms.

The number of research articles published each year is increasing so quickly that it is impossible for scientists to keep up with everything, observes team leader Pascal Friederich, who heads a KIT research group on artificial intelligence for materials sciences. While experienced scientists know how to find connections between research areas within their field, identifying links between these and other, unfamiliar topics is a different story.

The antimetastatic effects of calorie restriction are negated by voluntary exercise in an aggressive breast cancer mouse model

The role of lifestyle interventions in treatment success has become essential for nearly every disease. Healthy dietary habits, regular exercise, and stress management are key pillars that can improve quality of life during treatment, as well as delay disease onset and progression. In this study, we focus on the combination of mild calorie restriction (CR) and voluntary exercise as coadjuvants to chemotherapy in the treatment of triple-negative breast cancer using the 4T1 mouse model. In this model, voluntary exercise did not add benefits beyond chemotherapy plus CR in terms of primary tumor size, body composition, or physical performance, while dampening the antimetastatic effect of CR in the lungs of sedentary mice. These findings highlight the challenges of translating results from one preclinical model to another, and ultimately to humans.

Cell-by-cell analysis uncovers 345 risk genes across six neuropsychiatric disorders

The emergence of neuropsychiatric disorders, conditions that affect various brain functions and behaviors, is known to be driven by an intricate combination of factors. These can include both a genetic predisposition and exposure to traumatic events or other external circumstances.

Over the past decades, many neuroscience studies have tried to shed light on the origins of different mental health disorders. However, the biological, cellular and molecular mechanisms underpinning these disorders have not yet been clearly elucidated.

Researchers at Peking University Sixth Hospital and Peking University Institute of Mental Health recently analyzed genetic data collected from patients diagnosed with six different neuropsychiatric disorders, to better delineate the genes and cell types that contribute to their emergence. Their paper, published in Molecular Psychiatry, identifies 345 genes expressed in different types of cells that were linked to an increased risk of developing these disorders.

The Oscars bans generative AI in acting and writing categories

The Academy of Motion Picture Arts and Sciences—probably better known to the world as the Oscars folks—have drawn a firm line in the sand against the use of generative AI, changing its eligibility rules to exclude AI-generated performances and scripts.

The new rules, via The Wrap, state that in acting categories, only roles “demonstrably performed by humans with their consent” will be considered eligible for consideration, while in the writing categories, only “human-authored” screenplays will be eligible.

PCB prices have risen by up to 40% due to war in Iran, according to Reuters’ industry sources

According to “industry sources and executives” known to Reuters, the war in Iran is affecting the supply of materials that are crucial for Printed Circuit Boards (PCBs), which has made them shoot up in price. Reuters says that, cccording to Goldman Sachs, PCB prices in April shot up by as much as 40% since March.

According to the news agency, “Iran struck Saudi Arabia’s Jubail petrochemical complex in early April, forcing a halt in production of high-purity polyphenylene ether (PPE) resin—a critical base material used to ⁠manufacture PCB laminates.”

Metabolic inflammation at the adipose-brain axis

Adipose-brain axis in metabolic inflammation.

White adipose tissue (WAT) in addition to storing excess energy also releases cytokines, lipid mediators, adipokines, and extracellular vesicles that influence brain physiology.

The inflammatory mediators disrupt key brain interfaces, including the blood-brain barrier (BBB), perivascular and glymphatic clearance pathways, promoting endothelial dysfunction, altered astrocyte-pericyte support, impaired amyloid-b clearance, and region-specific glial activation.

In the brain, obesity-associated neuroinflammation leads to various neuronal dysfunction including cognition.

The authors discuss the role of adipokines in adipose-brain communication during obesity including how they contribute to neuroinflammation and synaptic dysfunction.

The authors also discuss therapeutic strategies targeting the adipose-brain axis, including exercise and dietary interventions and pharmacological approaches such as orlistat and incretin-based therapies. sciencenewshighlights ScienceMission https://sciencemission.com/adipose-brain-axis

Continue reading “Metabolic inflammation at the adipose-brain axis” | >

Oxford physicists achieve first-ever “quadsqueezing” breakthrough in quantum physics

Scientists have created a powerful new way to control quantum systems, achieving the first-ever demonstration of quadsqueezing—an elusive fourth-order quantum effect. By combining simple forces in a clever way, they made previously hidden quantum behaviors visible and usable, opening new frontiers for quantum technology.

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