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Scientists Find ‘Kill Switch’ That Activates Cancer Cell Death in The Lab

Year 2023 face_with_colon_three


Scientists have figured out a way to detonate the ‘doors’ that lead to the heart of cancerous tumors, blowing them wide open for drug treatments.

The strategy works by triggering a ‘timer bomb’ on the cells that line a tumor’s associated blood vessels.

These vessels control access to the tumor tissue, and until they are opened, engineered immune cells can’t easily gain entry to the cancer to fight it off.

Scientists discover on/off gene switches that could revolutionize personalized medicine

Year 2025 This could essentially end disease where the diseases would be edited off and the host repaired internally.


Scientists identified 473 human genes that act as genetic “on/off switches,” shaping disease risk through tissue-specific or universal patterns regulated by DNA changes and hormones.

Study: Switch-like gene expression modulates disease risk. Image Credit: gopixa / Shutterstock.

In a recent article published in Nature Communications, researchers analyzed methylomes, transcriptomes, and genomes from 943 individuals to characterize and identify genes that exhibit distinct on-off switches and explore their epigenetic and genetic regulation.

In utero exposure to NMDA receptor autoantibodies disrupts hippocampal circuit maturation

Majoros, Zhang, and Rahmati et al. identify a link between maternal autoimmunity and disrupted neuronal network development in the hippocampus of mice. In utero exposure to NMDA receptor autoantibodies impairs GABAergic signaling and early network synchrony in neonates, hindering the emergence of continuous hippocampal activity around eye opening.

Using moon dirt with 3D printing to build future lunar colonies

Simulated lunar dirt can be turned into extremely durable structures, potentially paving the way to more sustainable and cost-effective space missions, a new study suggests. Using a special laser 3D printing method, researchers melted fake lunar soil—a synthetic version of the fine dusty material on the moon surface, called regolith simulant—into layers and fused it with a base surface to manufacture small, heat-resistant objects.

If utilized on the lunar surface, the material may help build sturdy, nontoxic habitats and tools for future astronauts, capabilities that would be vital to the NASA Artemis missions that aim to establish a long-term human presence on the moon by the end of the decade.

But to assess how well this new construction material may work in space, the team tested their fabrication process under a range of different environmental conditions, revealing that the overall quality of the material depends greatly on the surface onto which the soil is printed.

Introduction to Quantum Electrodynamics (QED)

It’s now time to dig into quantum field theories with considerably more rigor than earlier in the series. First up is quantum electrodynamics, or QED. This was the first successful QFT, combining quantum mechanics and special relativity. Let’s learn what this model is all about, and how to do math with Feynman diagrams.

Script by andrew mattson, physics phd student at johns hopkins university.

Watch the whole Modern Physics playlist: http://bit.ly/ProfDavePhysics2

Classical Physics Tutorials: http://bit.ly/ProfDavePhysics1
Mathematics Tutorials: http://bit.ly/ProfDaveMaths.
General Chemistry Tutorials: http://bit.ly/ProfDaveGenChem.
Organic Chemistry Tutorials: http://bit.ly/ProfDaveOrgChem.
Biochemistry Tutorials: http://bit.ly/ProfDaveBiochem.
Biology Tutorials: http://bit.ly/ProfDaveBio.

EMAIL► [email protected].
PATREON► / professordaveexplains.

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Blood-brain barrier disruption, traumatic encephalopathy, and cognitive decline in retired athletes

Traumatic head injuries from collision and combat sports disrupt the blood-brain barrier and trigger inflammation for years after retirement, shows a new MRI and transcriptomic analysis of retired athletes.

Find out more in Science TranslationalMedicine.


Sci. Transl. Med. 18, eadu6037 (2026). DOI:10.1126/scitranslmed.adu6037

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