Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: electronics

Astrocytes are critical for fear memory

The team used a mouse model to understand how fear learning as a mechanism takes place in the brain, how fear-related memories can be retrieved, and the contribution of neurons versus astrocytes to fear learning.

Using fluorescent activity sensors, the team watched astrocytes respond in real time as fear memories were formed and later retrieved. As those memories were extinguished, astrocyte activity diminished. When the researchers then selectively increased or suppressed the signals astrocytes send to neighboring neurons, the strength of fear memories shifted in parallel, demonstrating that astrocytes are not just passive bystanders, but active participants in shaping fear.

Change in astrocyte activity also influenced neural circuits. When the astrocyte activity was disrupted, neurons could no longer form normal fear-related activity patterns and effectively transmit information about appropriate defensive reactions to brain regions that help control defensive behavior. These findings challenge neuron-centric models of fear by showing that fear memories aren’t produced by neurons alone.

The impact of disrupting astrocytes rippled beyond the amygdala. The manipulations also influenced how fear signals were relayed to the prefrontal cortex, a brain region that is key for decision-making. This suggests that astrocytes not only influence encoding of fear memories by the amygdala, but also how the brain uses those memories to determine appropriate responses to fearful situations.

Knowing that astrocytes play a key role in the retrieval of fear memories will reshape therapeutic interventions for disorders driven by persistent fearful memories such as post-traumatic stress disorder, anxiety disorders and phobias, the author said. If astrocytes help determine whether fear memories are expressed or successfully extinguished, then targeting astrocyte-related pathways, rather than neural pathways, could eventually complement neuron-focused therapies.

Picture a star-shaped cell in the brain, stretching its spindly arms out to cradle the neurons around it. That’s an astrocyte, and for a long time, scientists thought its job was caretaking the brain, gluing together neurons, and maintaining neural circuits.

Continue reading “Astrocytes are critical for fear memory” | >

Sea urchin spines inspire self-powered underwater sensors

Nature does it again! The natural world has a knack for giving us the blueprints for some useful technologies, and the humble sea urchin is the latest contributor. Scientists have designed a new class of smart sensors by mimicking the internal architecture found in their spines.

Sea urchins are covered in movable spines that have long been thought of as a form of deterrent and protection against predators. But according to a new study published in the journal Nature, they are also sophisticated sensing tools.

Shield and sensor.

New diamond growth method slashes device temperatures by 41°F

What started as a fun experiment to create a decorative diamond “owl” for distinguished guests has evolved into a scalable manufacturing process for electronics.

Researchers at Rice University have developed a bottom-up method for growing patterned diamond surfaces to cool electronics.

The technique enables diamonds to be integrated directly into devices, reducing operating temperatures by 23°C (41°F).

1Campaign platform helps malicious Google ads evade detection

A newly identified cybercrime service known as 1Campaign is enabling threat actors to run malicious Google Ads that remain online for extended periods while evading scrutiny from security researchers.

1Campaign is a cloaking service that passes Google’s screening process and shows malicious content only to real potential victims. Security researchers and automated scanners are served benign white pages.

The operation has been active for at least three years and is managed by a developer using the name ‘DuppyMeister,’ according to a report from data security company Varonis.

The IceCube experiment is ready to uncover more secrets of the universe

The name “IceCube” not only serves as the title of the experiment, but also describes its appearance. Embedded in the transparent ice of the South Pole, a three-dimensional grid of more than 5,000 extremely sensitive light sensors forms a giant cube with a volume of one cubic kilometer. This unique arrangement serves as an observatory for detecting neutrinos, the most difficult elementary particles to detect.

In order to detect neutrinos, they must interact with matter, creating charged particles whose light can be measured. These light measurements can be used to determine information about the properties of neutrinos. However, the probability of neutrinos interacting with matter is extremely low, so they usually pass through it without leaving a trace, which makes their detection considerably more difficult.

For this reason, a large detector volume is required to increase the probability of interaction, and state-of-the-art technology is crucial for detecting such rare interactions.

IceCube upgrade adds six deep sensor strings to detect lower-energy neutrinos

Since 2010, the IceCube Observatory at the Amundsen-Scott South Pole Station has been delivering groundbreaking measurements of high-energy cosmic neutrinos. It consists of many detectors embedded in a volume of Antarctic ice measuring approximately one cubic kilometer. IceCube has now been upgraded with new optical modules to enable it to measure lower-energy neutrinos as well. Researchers at the Karlsruhe Institute of Technology (KIT) made a significant contribution to this expansion.

IceCube serves to measure high-energy neutrinos in an ice volume of one cubic kilometer. As neutrinos themselves do not emit any signals, the tracks of muons and other secondary particles are measured precisely. Muons are elementary particles sometimes produced by the interaction of neutrinos with ice. Contrary to neutrinos, muons carry an electric charge. On their way through the ice, they produce a characteristic light cone, which is detected by highly sensitive detectors.

Now, 51 researchers from around the world have installed six new strings of novel sensors up to 2,400 meters deep into the eternal ice, thereby expanding the IceCube experiment to also measure low-energy neutrinos.

New laser “comb” can enable rapid identification of chemicals with extreme precision

Researchers demonstrated a broadband infrared frequency comb that can operate stably, efficiently, and accurately without the need for bulky external components. The device could be utilized in a remote sensor or portable mass spectrometer that can track and monitor multiple chemicals in real-time for extended periods.

/* */