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Jun 22, 2018

Accurate measurements of sodium intake confirm relationship with mortality

Posted by in categories: biotech/medical, food

Eating foods high in salt is known to contribute to high blood pressure, but does that linear relationship extend to increased risk of cardiovascular disease and death? Recent cohort studies have contested that relationship, but a new study published in the International Journal of Epidemiology by investigators from Brigham and Women’s Hospital and their colleagues using multiple measurements confirms it. The study suggests that an inaccurate way of estimating sodium intake may help account for the paradoxical findings of others.

“Sodium is notoriously hard to measure,” said Nancy Cook, ScD, a biostatistician in the Department of Medicine at BWH. “Sodium is hidden—you often don’t know how much of it you’re eating, which makes it hard to estimate how much a person has consumed from a dietary questionnaire. Sodium excretions are the best measure, but there are many ways of collecting those. In our work, we used multiple measures to get a more accurate picture.”

Sodium intake can be measured using a spot test to determine how much salt has been excreted in a person’s urine sample. However, in urine can fluctuate throughout the day so an accurate measure of a person’s on a given day requires a full 24-hour sample. In addition, sodium consumption may change from day to day, meaning that the best way to get a full picture of sodium intake is to take samples on multiple days.

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Jun 21, 2018

This Table Saw Could Save Your Fingers From Getting Amputated

Posted by in category: futurism

Sawed-off fingers are a thing of the past with this technology. Here’s how SawStop does it. (via @ Seeker)

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Jun 21, 2018

‘Stealth sheet’ hides hot objects from prying infrared eyes

Posted by in categories: drones, materials

Infrared cameras are the heat-sensing eyes that help drones find their targets, even in the dead of night or through heavy fog.

Hiding from such detectors could become much easier, thanks to a new cloaking material that renders objects—and people—practically invisible.

“What we have shown is an ultrathin stealth ‘sheet.’ Right now, what people have is much heavier metal armor or thermal blankets,” says Hongrui Jiang, the Lynn H. Matthias Professor and Vilas Distinguished Achievement Professor of electrical and computer engineering at the University of Wisconsin-Madison.

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Jun 20, 2018

The Limits of Neuroplasticity in the Brain

Posted by in categories: biological, neuroscience, science

New research shows that the brain‘s neuroplasticity isn’t as flexible as previously thought.

One of the brain’s mysteries is how exactly it reorganizes new #information as you learn new tasks. The standard to date was to test how neurons learned new behavior one #neuron at a time.

Carnegie Mellon University and the University of Pittsburgh decided to try a different approach. They looked at the population of neurons to see how they worked together while #learning a new behavior. Studying the intracortical population activity in the primary motor cortex of rhesus macaques during short-term learning in a brain–computer interface (BCI) task, they were able to study the reorganization of population during learning.

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Jun 19, 2018

Cataract Removal Surgery

Posted by in category: biotech/medical

How surgeons remove cataract from the eye.

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Jun 17, 2018

The most important lesson from 83,000 brain scans

Posted by in category: neuroscience

Never miss a talk! SUBSCRIBE to the TEDx channel: http://bit.ly/1FAg8hB

In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)

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Jun 17, 2018

Harvard Rewinds the Biological Clock of Time

Posted by in categories: bioengineering, biological, DNA, health, life extension, science, transhumanism

Investigators at Harvard Medical School have identified the key cellular mechanisms behind vascular aging and its effects on muscle health, and they have successfully reversed the process in animals.

The scientists used a chemical compound that’s an NAD+ booster called NMN which plays a critical role in repairing cellular DNA as well as maintaining cell vitality to test what would happen.

Could reversing the aging of blood vessels hold the key to restoring youthful vitality? If the old adage “you are as old as your arteries” reigns true then the answer is yes, at least in mice.

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Jun 16, 2018

Probiotics may help boost mood and cognitive function

Posted by in categories: biotech/medical, health, neuroscience

Probiotics can do more than improve your gut health. They also may indirectly enhance your brain, too.

Research shows that the gut and brain are connected, a partnership called the gut-brain axis. The two are linked through biochemical signaling between the nervous system in the digestive tract, called the enteric nervous system, and the central nervous system, which includes the brain. The primary information connection between the brain and gut is the vagus nerve, the longest nerve in the body.

The gut has been called a “second brain” because it produces many of the same neurotransmitters as the brain does, like serotonin, dopamine, and gamma-aminobutyric acid, all of which play a key role in regulating mood. In fact, it is estimated that 90% of serotonin is made in the digestive tract.

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Jun 13, 2018

Lentils significantly reduce blood glucose levels, study reveals

Posted by in categories: biotech/medical, food, health

Replacing potatoes or rice with pulses can lower your blood glucose levels by more than 20 per cent, according to a first-ever University of Guelph study.

Prof. Alison Duncan, Department of Human Health and Nutritional Sciences, and Dan Ramdath of Agriculture and Agri-Food Canada, found that swapping out half of a portion of these starchy side dishes for can significantly improve your body’s response to the carbohydrates.

Replacing half a serving of rice with lentils caused to drop by up to 20 per cent. Replacing potatoes with lentils led to a 35-per-cent drop.

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Jun 9, 2018

Human Skeletal Muscle Aging and Mutagenesis

Posted by in categories: aging, DNA, genetics, health, life extension

Study based upon human skeletal muscle aging, mutagenesis, and the role of #satellite cells.

“A more comprehensive understanding of the interplay of stem cell–intrinsic and extrinsic factors will set the stage for improving cell therapies capable of restoring tissue homeostasis and enhancing muscle repair in the aged.”

Human aging has multiple effects on the human body. One of the effects of human aging is the reduction in skeletal muscle (SkM) function and a reduction in the number and activity of satellite cells (SCs), the resident stem cells. The whole genome of single SC clones of the leg muscle vastus lateralis from healthy individuals of different ages (21–78 years) was analyzed, to study the specific connection between SC aging and muscle impairment. In healthy adult muscle rapid increase of SCs is consistent with the accumulation rate of 13 somatic mutations per genome per year. Mutations typically do not happen in SkM-expressed genes because they are protected. However, as mutations in exons and promoters increase, genes involved in SC activity and muscle function are targeted which results in aging. Exons are coding sections of an RNA transcript, or the DNA encoding it, that are translated into protein. Proteins are the synthesis of molecules. A change in of a single base pair that caused the substitution of a different amino acid in the resulting protein (missense mutation) that was propagated to the muscle and detected in association with SC mutations affecting the whole tissue. #Somatic mutagenesis in SCs as a result is the driving force in the age related decline of SkM function.

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