Lifeboat Foundation

An extraordinarily promising new technique using ultrasound to clear the toxic protein clumps thought to cause dementia and Alzheimer’s disease is moving to the first phase of human trials next year. The innovative treatment has proven successful across several animal tests and presents an exciting, drug-free way to potentially battle dementia.

A remarkable new implantable device developed by engineers at University of Wisconsin–Madison promises a new way to battle obesity. By gently stimulating a nerve that links the stomach to the brain, the device tricks your brain into thinking you’re full.

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Tag your bestie if you’ve ever “been on the same wavelength.”

New research examines cognitive function and brain atrophy in both people with and without type 2 diabetes over the course of approximately 5 years.

Why your brain is like an ant colony: they both get wiser and more stable by using collective memory for learning.

When it comes to recovering from insult, the adult human brain has very little ability to compensate for nerve-cell loss. Biomedical researchers and clinicians are therefore exploring the possibility of using transplanted nerve cells to replace neurons that have been irreparably damaged as a result of trauma or disease. However, it is not clear whether transplanted neurons can be integrated sufficiently, to result in restored function of the lesioned network. Now researchers at the Max Planck Institute of Neurobiology in Martinsried, the Ludwig Maximilians University Munich, and the Helmholtz Zentrum München have demonstrated that, in mice, transplanted embryonic nerve cells can indeed be incorporated into an existing network and correctly carry out the tasks of damaged cells originally found in that region.

Neurodegenerative diseases such as Alzheimer’s or Parkinson’s disease, but also stroke or certain injuries lead to a loss of brain cells. The mammalian brain can replace these cells only in very limited areas, making the loss in most cases a permanent one. The transplantation of young nerve cells into an affected network of patients, for example with Parkinson’s disease, allow for the possibility of a medical improvement of clinical symptoms. However, if the nerve cells transplanted in such studies help to overcome existing network gaps or whether they actually replace the lost cells, remained unknown.

In the joint study, researchers of the Max Planck Institute of Neurobiology, the Ludwig Maximilians University Munich, and the Helmholtz Zentrum München have specifically asked whether transplanted embryonic nerve cells can functionally integrate into the visual cortex of adult mice. The study was supported by the center grant (SFB) 870 of the German Research Foundation (DFG). “This brain region is ideal for such experiments,” says Magdalena Götz, joint leader of the study together with Mark Hübener, who continues to explain: “By now, we know so much about the functions of the nerve cells in the visual cortex and the connections between them that we can readily assess whether the new nerve cells actually perform the tasks normally carried out by the network.”

People with depression also tend to “visit primary care physicians more often than others,” explains Prof. Lorenzo-Luaces. “They have more medical problems, and their depression sometimes gets in the way of their taking their medication for other medical problems.”

So, for the new review, the team examined 21 existing studies using meta-regression analysis. The analysis concluded that CBT apps were effective for treating mild, moderate, and severe depression.

Some of the trials included in the review compared a CBT app with a sham app. In these studies, the real apps were also significantly more effective at treating depression.

The human brain needs to suppress obvious ideas in order to reach the most creative ones, according to scientists at Queen Mary University of London and Goldsmiths, University of London.

Creativity requires us to break away from more common and easily reached ideas but we know little about how this happens in our brain.

A new study, published in the Proceedings of the National Academy of Sciences, shows that brainwaves play a crucial role in inhibiting habitual thinking modes to pave the way to access more remote ideas.

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