Lifeboat Foundation

Always hungry 🙈.

By Christian Jarrett. Researchers provoked curiosity in their volunteers using magic and obscure trivia questions.

Open brain surgery is about as dangerous as it sounds, but for sufferers of conditions like Parkinson’s and epilepsy it can be the only way to relieve their symptoms. Unfortunately, this means drilling a hole in the skull and stimulating the brain with electrical currents, bringing on the risk of serious side effects. Fortunately, scientists have opened a new doorway to the brain, developing the Stentrode, a promising first-of-a-kind device that can deliver the currents to targeted areas through a small keyhole incision in the neck.

The discovery of brain structures that apparently mark time has raised a larger question: What is time, anyway?

Scientists can now discover how the fine details of gene activity differ from one cell type to another in a tissue sample, thanks to a technique invented by Weill Cornell Medicine researchers.

The technique, described in a paper published Oct. 15 in Nature Biotechnology, will enable biologists to better understand the distinct molecular workings of different cell types in the body. It may also enable the improved understanding and treatment of diseases caused by abnormal gene activity.

“An individual gene can ‘say’ different things, and the true meaning often requires listening to entire phrases, rather than single words,” said senior study author Dr. Hagen U. Tilgner, assistant professor of neuroscience in the Feil Family Brain and Mind Research Institute at Weill Cornell Medicine. “Our new method essentially allows us to record complete phrases, called isoforms, that each gene expresses in each cell.”

Experts claim that this new breakthrough could significantly halt the growth of brain tumours.

Probing the brain is brutal work.

It’s a start for developing novel therapies.

• Once dismissed as a “party drug,” ketamine is emerging as a potential alternative treatment for depression.
• A growing list of academic medical centers now offer the drug, including Columbia University, which began offering ketamine to patients with severe depression this fall.
• Ketamine works differently from common antidepressants like Celexa or Prozac and has been called “the most important discovery in half a century.”
• Pharmaceutical companies, including Allergan and Johnson & Johnson, are also working on developing blockbuster antidepressants inspired by ketamine.

Ketamine, a drug once associated with raucous parties, bright lights, and loud music, is increasingly being embraced as an alternative depression treatment for the millions of patients who don’t get better after trying traditional medications.

The latest provider of the treatment is Columbia University, one of the nation’s largest academic medical centers.

Showrunner Jeff Buhler has built a fascinating world around Martin’s story seeds, starting by setting the action within the foreseeable future, rather than in an incomprehensibly distant one. The invented technologies here are particularly intriguing, like the genetic modifications first officer Melantha Jhirl (Jodie Turner-Smith) has to make her better suited for space travel, or the cybernetics technician Lommie (Maya Eshet) uses to interface with machinery. Given the state of real-world technological developments in genetic engineering and research into brain-machine interfaces, the series feels plausible and grounded, even though it’s set in a spacefaring future.

The 10-episode space series adapts a 40-year-old George R.R. Martin novella.

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