Lifeboat Foundation

A new proof-of-concept study has found a combination of two drugs, already approved by the FDA for other uses, may boost the release of stem cells from bone marrow and accelerate the healing of broken bones. Only demonstrated in animals at this stage, the researchers suggest clinical trials could progress rapidly considering the drugs have already been demonstrated as safe in humans.

“The body repairs itself all the time,” says corresponding author on the study Sara Rankin. “We know that when bones break they will heal, and this requires the activation of stem cells in the bone. However, when the damage is severe, there are limits to what the body can do of its own accord.”

A great deal of current research is focusing on mesenchymal stem cell (MSC) therapies. MSCs are a type of adult stem cell that can grow into a variety of different cell types including muscle, fat or bone. Many current MSC treatments in development involve extracting a small number from a patient, growing them in laboratory conditions, then injecting them back into the patient.

A surprising star collision is making scientists rethink what they know about the universe.

For the first time, researchers have used light to control the shape of nanoparticles and create micron-size hollow shells from crystals of cuprous oxide (copper and oxygen). Such particles could have future applications as a low-cost catalyst to help pull excess carbon dioxide from the air, a way to improve microscopic imaging and more, says Bryce Sadtler, a chemist at Washington University in St. Louis and senior author of a study on the new method, published last October in Chemistry of Materials.

Hollowed-out microcrystals could lock away carbon.

The US Navy has successfully installed its first Optical Dazzling Interdictor, Navy (ODIN) laser weapon aboard one of its warships. During dry-dock operations, the Arleigh Burke-class guided-missile destroyer USS Dewey (DDG 105) received the stand-alone laser system, which is designed to blind the sensors on Unmanned Aerial Systems (UAS).

The ODIN laser isn’t the first to be deployed on a US Navy warship. That honor goes to the Office of Naval Research’s (ONR) Laser Weapon System (LaWS), which was deployed on the USS Ponce (LPD-15) in 2014. However, this experience by the team behind LaWS at the Naval Surface Warfare Center (NSWC) Dahlgren Division provided the expertise needed to complete the development of ODIN.

Unlike other laser weapons that are designed to destroy targets with blasts of concentrated laser light, ODIN is what is known as a dazzler laser. That is, it’s one of a class of lasers that are intended to blind or distract rather than destroy. Though the legality of using such lasers against human pilots restricts them to only distracting the person by acting like the glare of oncoming headlamps, such lasers can also disable or destroy delicate optical sensors on drones.

Last year we ogled the Newron EV-1 electric motorcycle upon its debut, but questioned whether it would ever make it to market. As of today though, the company has ended speculation by opening pre-orders for the highly unique, wooden-bodied electric motorcycle.

Using this technique, the researchers were able to reduce tumour size in mice by between eight and nine times without harming healthy tissue. In the future, the team hopes to test this new therapy on patients with melanoma.

Superfluid helium, describable by a two-component order parameter, exhibits only the Bogolubov mode with energy $\to 0$ at long wavelengths, while a Lorentz-invariant theory with a two-component order parameter exhibits a finite energy mode at long wavelengths (the Higgs Boson), besides the above mass-less mode. The mass-less mode moves to high energies if it couples to electromagnetic fields (the Anderson-Higgs mechanism). Superconductors, on the other hand have been theoretically and experimentally shown to exhibit both modes. This occurs because the excitations in superconductors have an (approximate) particle-hole symmetry and therefore show a similarity to Lorentz-invariant theories.

Dev Genes Evol. 2012 Mar;222:29–44. doi: 10.1007/s00427-011‑0387-z. Epub 2012 Feb 23.

Gap junctional proteins are important components of signaling pathways required for the development and ongoing functions of all animal tissues, particularly the nervous system, where they function in the intracellular and extracellular exchange of small signaling factors and ions. In animals whose genomes have been sufficiently sequenced, large families of these proteins, connexins, pannexins, and innexins, have been found, with 25 innexins in the nematode Caenorhabditis elegans Starich et al. (Cell Commun Adhes 8: 311–314, 2001) and at least 37 connexins in the zebrafish Danio rerio Cruciani and Mikalsen (Biol Chem 388:253–264, 2009). Having recently sequenced the medicinal leech Hirudo verbana genome, we now report the presence of 21 innexin genes in this species, nine more than we had previously reported from the analysis of an EST-derived transcriptomic database Dykes and Macagno (Dev Genes Evol 216: 185–97, 2006); Macagno et al. (BMC Genomics 25:407, 2010).

Plastic has become ubiquitous in our home and work lives over the past 50 years. It is pliable, durable, easy to make, and hard to break. Plastic may be convenient and useful, but it also won’t break down naturally, which makes it a long-lasting pollutant. A recent study published in Science Advances found that humans have produced 8,300 million metric tons of plastic to date, which is 25,000 times the weight of the Empire State Building. Seventy nine percent of that has ended up in landfills or the ocean. If we continue making plastic at our current rate, that figure will reach 12,000 metric tons by the year 2050. Plastic pollutants are showing up in drinking water all over the world as well as in food products, like beer. We have a serious problem.

Humans are “addicted” to plastic, says Gavin McIntyre, chief scientist and co-founder of Ecovative, a company aiming to reduce our dependence on plastic and other toxic or non-decomposable materials by making biodegradable alternatives. For several years, Ecovative has been manufacturing eco-friendly packaging supplies, and has just received a grant from the Environmental Protection Agency to further develop its new product, mResin, an alternative to the harmful adhesives found in most paneling and insulation.

Ecovative products, unlike most synthetic plastics that are made from crude oil, are grown from mycelium—networks of fungal or mushroom roots. In nature, fungi break down waste, such as old leaves, dead plants, and pieces of wood, and use it to propagate. Ecovative harnesses this natural process and grows the mycelium into various shapes and structures, from pieces of furniture to packaging materials like MycoFoam, its trademarked Styrofoam substitute.