Lifeboat Foundation

As we age, our bones become thinner, we suffer fractures more often, and bone-diseases such as osteoporosis are more likely to occur. One responsible mechanism involves the impaired function of the bone-marrow stem cells, which are required for the maintenance of bone integrity. Researchers from the Max Planck Institute for Biology of Ageing and CECAD Cluster of Excellence for Ageing Research at the University of Cologne have now shown that the reduced stem cell function upon aging is due to changes in their epigenome. They were able to reverse these changes in isolated stem cells by adding acetate. This fountain of youth for the epigenome could become important for the treatment of diseases such as osteoporosis.

Aging Researchers have been looking at epigenetics as a cause of aging processes for some time. Epigenetics looks at changes in genetic information and chromosomes that do not alter the sequence of the genes themselves, but do affect their activity. One possibility is changes in proteins called histones, which package the DNA in our cells and thus control access to DNA. The Cologne research group of Peter Tessarz has now studied the epigenome of mesenchymal stem cells. These stem cells are found in bone marrow and can give rise to different types of cells such as cartilage, bone and fat cells.

The website is eye-catching for its simplicity. Against a white backdrop, a giant blue button invites visitors to upload a picture of a face. Below the button, four AI-generated faces allow you to test the service. Above it, the tag line boldly proclaims the purpose: turn anyone into a porn star by using deepfake technology to swap the person’s face into an adult video. All it requires is the picture and the push of a button.

MIT Technology Review has chosen not to name the service, which we will call Y, or use any direct quotes and screenshots of its contents, to avoid driving traffic to the site. It was discovered and brought to our attention by deepfake researcher Henry Ajder, who has been tracking the evolution and rise of synthetic media online.

With all that said, it’s natural for humans to crave and eat limited amounts of sugar. After going through all the research, here’s what I am doing for myself.

For example, foods high in fructose stimulate ghrelin while suppressing leptin—hormones responsible for hunger and satiety. Sugar can promote chronic hyperglycemia, which can both lead to weight gain and is another risk for diabetes. And sugary drinks, especially, are tied directly to obesity.

Sugar and aging: a bad combination (so what should we do?)

Continue reading “Sugar and Aging: What You Need to Know” »

This is an emerging therapeutic technique that works by targeting the underlying causes of a disease, rather than the symptoms it causes. It does this by targeting a particular gene, and preventing it from making the protein that it produces.

The United Kingdom’s NHS has very recently approved a new cholesterol-lowering jab which will be offered to 300,000 people over the next three years.

The drug – inclisiran – will be administered twice a year as an injection.

Continue reading “A Clever ‘Gene Silencing’ Injection Has Been Approved For Treating High Cholesterol” »

X-Prize board member Sergey Young on his new book, and the potential for a longevity X-Prize.

“We have created science and technology to extend our life, but we haven’t created life we want to extend.”–Sergey Young, Seeking Delphi™ episode #55, explaining why he believes more people do not support radical life extension.

Continue reading “#55: The Longevity Dialogs Part 3, The Science and Technology of Growing Young with Sergey Young” »

This could lead to clothing made from real muscle. That might sound like an unsettling option, but the fibers aren’t what you’re imagining.

Physicists at The Australian National University (ANU) have developed extremely powerful microscopic lasers that are even smaller than the wavelength of the light they produce. So called ‘nanolasers’ have a huge variety of medical, surgical, industrial and military uses, covering everything from hair removal to laser printers and night-time surveillance. According to lead researcher Professor Yuri Kivshar, the nanolasers developed by his team promise to be even more powerful than existing lasers, allowing them to be useful in smaller-scale devices. “They can also be integrated on a chip,” he said.

One of the many areas graphene promises to have transformative effects is in fortifying construction materials like concrete and asphalt. A first-of-a-kind trial now underway seeks to apply the wonder material’s impressive attributes to one of the UK’s major thoroughfares, by deploying it in a road resurfacing project along a stretch of the A1 motorway.

Made up of a single sheet of carbon atoms arranged in a honeycomb pattern, graphene offers incredible strength and flexibility, and by incorporating it into materials like asphalt scientists hope to develop road surfaces that last far longer, and therefore cost less to maintain.

Back in 2017 we looked at an interesting take on this from a pair of Italian companies that developed an asphalt material doped with a graphene additive to make it less likely to soften in the heat and crack in the cold under high loads. This product, known as Gipave, also incorporates plastic pellets and was recently rolled out along stretches of UK roads as part of trials to see how it can extend the lifespan of the surface.

California-based startup Relativity Space is manufacturing rockets using giant Westworld-esque 3D printers, a process they say could drastically shorten the rocket-making process from years to weeks. Tim Ellis, the company’s 30-year-old CEO, explains how the high degree of automation in Relativity’s factory has enabled them to build rockets remotely during the Covid-19 pandemic.

#Coronavirus #Space #HelloWorld.
——-
Like this video? Subscribe to Bloomberg on YouTube: https://www.youtube.com/Bloomberg?sub_confirmation=1
Become a Quicktake Member for exclusive perks: https://www.youtube.com/bloomberg/join.

Continue reading “The SpaceX Competitor is Printing Its Rockets” »