Approximately 4 of 10 cancer cases in 2022 may have been averted by avoiding exposure to key preventable risk factors, according to findings from a global analysis study published in Nature Medicine.1
Of 18.7 million cancer cases recorded in 2022, approximately 7.1 million (37.8%) were linked to modifiable risk factors. Cancer cases due to modifiable risk factors were reported in 29.7% of women with cancer compared with 45.4% of men. The highest cancer burden for female populations was observed in sub-Saharan Africa, where 38.2% of cases were linked to modifiable risk factors; male populations experienced the highest burden in East Asia, where 57.2% of cases were associated with such risk factors.
Across the world, new cancer cases in women were typically linked to infections (11.5%), smoking (6.3%), and high body mass index (BMI; 3.4%). Among men, the most common risk factors associated with cancer cases included smoking (23.1%), infections (9.1%), and alcohol consumption (4.6%).