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Existing compound produces pain-relieving effects and relieves anxiety. Past pain research typically has focused upon the spinal cord or the peripheral areas of the nervous system located outside the spinal cord and brain. However, a research team headed by Volker E. Neugebauer, M.D., Ph.D., at the Texas Tech University Health Sciences Center (TTUHSC) School of Medicine recently investigated how some mechanisms in the brain contribute to pain. His study, “Amygdala group II mGluRs Mediate the Inhibitory Effects of Systemic Group II mGluR Activation on Behavior and Spinal Neurons in a Rat Model of Arthritis Pain,” was published recently by the journal Neuropharmacology. Mariacristina Mazzitelli, a TTUHSC research assistant and Ph.D. candidate, is the study’s lead author.

“Our group has been interested in understanding pain mechanisms, and our unique area of expertise is really understanding that changes in the brain contribute to the persistence, intensity and other side effects of pain,” Neugebauer said. “It is not just a sensation that let’s you know where it hurts and how intense the pain feels. It also causes anxiety, impairs quality of life and causes depression. We’re studying the brain because all of those things reside there.”

To better understand what pain-related changes may occur in the brain, and how to normalize those changes, Neugebauer’s study applied an arthritis pain model and focused on the amygdala, which are almond-shaped clusters located deep inside each of the brain’s temporal lobes. The amygdala is part of what is known as the limbic brain, a complex arrangement of nerve cells and networks that control basic survival functions, motivations and emotions like fear and play a central role in disorders like anxiety, addiction and pain.

I am chronically old, but I am not old. I was on dancing with the stars. This is the new way to age. It’s not that old paradigm that says you wrinkle, frail, hunch over, have heart and other illnesses, be in a nursing home. No, there is a new paradigm. I’m the new paradigm. The older I get, the stronger and better my brain gets. I fully expect to be on the Vegas stage when I am 80.

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https://www.ncbi.nlm.nih.gov/pubmed/25301715

What happens in the brain and body in the moments after cardiac arrest?

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Recently, an 82-year-old woman who suffered from dementia, who couldn’t recognize her own son has miraculously got her memory back after changing her diet.

When his mother’s condition became so severe that for her own safety she had to be kept in the hospital, Mark Hatzer almost came to terms with losing another parent.

Customers can trim branches for $35 a pound or cut down the whole plant (like a Christmas tree) for $25 a pound. In a video of the field’s grand opening, a customer buys a 15-pound plant for almost $400.

That may sound pricey, but considering you’re lucky to find most refined hemp products for $25 an ounce, it’s a bargain, according to the farm’s customers, who tell the local newspaper, they’ll be using the plant’s flowers to make CBD oil, lotions and tinctures for pain, anxiety, depression and insomnia.

Instead of conventional row crops, they now grow one of the most lucrative plants on the planet.

Continue reading “USA’s First ‘Pick-Your-Own Hemp’ Field Opens in Maine” »

How is a Unitary Subject of Experience Possible? ~ Philosopher David Pearce.

Is Australia conscious? How would 86 billion classical neurons (mind dust) come together to form a unitary subject of experience?
The answer is related to the binding problem of consciousness.

Continue reading “David Pearce — Unitary Subjects of Experience & the Binding Problem of Consciousness” »

A stroke occurs when blood flow to an area of the brain is suddenly cut off. The brain cells get deprived of oxygen and begin to die quickly. Having a stroke is a scary thought, but you can be mindful of your health to reduce the chances of having one.

Wow!

Brain Computer interface technology opens up a world of possibilities. We are on the cusp of this technology that is so powerful and has the potential to so radically transform our lives and existence! After starting three venture-funded startups in Silicon Valley, Steven Hoffman, known as Captial Hoff, launched Founders Space with the mission to educate and accelerate entrepreneurs and intrapreneur. Founder Space has become one of the top startup accelerators in the world with over 50 partners in 22 countries. This talk was given at a TEDx event using the TED conference format but independently organized by a local community.

A collaborative study published today in the journal Cell Reports provides evidence for a new molecular cause for neurodegeneration in Alzheimer’s disease. The study, led by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, integrates data from human brain autopsy samples and fruit flies to reveal a novel mechanistic link between alterations in RNA splicing and tau-mediated neurodegeneration in Alzheimer’s disease.

“Cells carry out their functions by producing specific proteins encoded in their genes. To produce proteins, genes encoded in the DNA are first transcribed into RNA molecules, which subsequently are translated into proteins,” said corresponding author Dr. Joshua Shulman, associate professor of neurology, neuroscience and molecular and human genetics at Baylor and investigator at the Jan and Dan Duncan Neurological Research Institute.

In this study, Shulman and his colleagues investigated a molecular mechanism called RNA splicing that is involved in the production of mature RNA molecules necessary to produce working proteins. They looked into the possibility that aggregates of tau protein within neurons, a key marker of Alzheimer’s disease, interfered with RNA splicing.