Lifeboat Foundation

A bionic revolution is brewing, as recent advancements in bioengineering have brought about scientific breakthroughs in rehabilitation for people with disabilities. The most cutting edge research is happening inside the human brain, where implanted technology allows people to communicate directly with computers, using their thoughts.

VICE’s Wilbert L. Cooper travels to Zurich to see the first-ever bionic Olympics and discovers a host of technologies that are expanding what it means to be human.

Continue reading “How Bionic Limbs Are Changing Lives | VICE on HBO” »

Atherosclerosis progresses is driven by chronic inflammation, the more sources of low-grade, smoldering inflammation, the faster atherosclerosis could develop. Gum disease is one such source of inflammation and is associated with a higher incidence of strokes.

Patients with gum disease were three times as likely to have a stroke involving blood vessels in the back of the brain, which controls vision, coordination and other vital bodily functions; and.

Built on decades of previous research, a team from the University of Wisconsin-Madison teased out a tiny chunk of brain tissue within the thalamus, a nub above the brain stem, as a critical part of NCC. As proof of concept, they gave it several bouts of electrical shocks, and restored awareness in unconscious monkeys under heavy anesthesia.

The crux? As soon as the electrical stimulation stopped, the monkeys’ awareness also slipped away.

Although the thalamus has long been thought of as somehow involved in supporting consciousness, the study is one of the first to pinpoint exact neural circuits—highways between the thalamus and parts of the cortex—as “switches” for consciousness that we can control using brain stimulation. And that’s wonderful news for comatose patients.

But apart from a few small-scale examples, the only stem cell-based medical treatment practised in clinics uses haematopoietic stem cells found in the blood and bone marrow – which only produce blood cells – for transplants in blood cancer patients. These cells are taken from a patient’s sibling or an unrelated donor, before being infused into a patient’s blood, or they’re taken from a patient’s own blood before being reinfused. The procedure has been used to treat blood malignancies for almost half a century, and recently multiple sclerosis too. So how likely is it that the predictions about stem cells’ longevity-enhancing powers will become a reality?

Startups are offering stem cells as the cure to everything from age-related illness to wrinkles. But the science is far from clear-cut.

Optical technologies that can be used to modulate neuronal activity are opening up exciting possibilities for research in neuroscience and biology. Optical tools allow neuroscientists to excite and inhibit neurons or areas of the brain at will. They can thus be used to investigate the function of specific brain circuits or regions, as well as to identify new potential treatments for neurological and psychiatric diseases.

The generation of tethered azobenzene photoswitches targeted at membrane bilayers or linked to ion channels is a pioneering optical technique that could further aid the study of the human brain. This technique, however, particularly when implemented at high light intensities, can lead to a considerable increase in temperature and can thus be harmful to neurons when used repeatedly.

To overcome this limitation, researchers at the Italian Institute of Technology (IIT) in collaboration with Politecnico di Milano, have recently created a new light-sensitive azobenzene compound, dubbed Ziapin2, which can be used to build photoswitches that do not increase in temperature when irradiated with visible light. This new compound, introduced in a paper published in Nature Nanotechnology, partitions into the plasma membrane with a high stability, enabling its thinning and an increased capacitance at a steady state.

There are more theories than facts about polyglots. Because internet lists of polyglots identify mainly men, there’s the belief that the male brain is more predisposed to multilingualism. Others believe that polyglots are disproportionately gay and/or left-handed.

These unfounded theories infuriate Ev Fedorenko, a cognitive neuroscientist at the Massachusetts Institute of Technology (MIT). Her lab is conducting a study seeking to dispel them and establish a basic understanding of how the polyglot brain works.

Recently, a polyglot named Susanna Zaraysky submitted to a two-hour session of tests inside an fMRI machine. Zaraysky speaks nine languages, most of them the usual suspects — French, Spanish, Portuguese, Russian — but also Ladino, the version of Spanish spoken by Jews who were expelled from Spain in the 15th century.

In his book, Paul Henry Wand, MD, describes a protocol for treating concussions.

By Paul Henry Wand, MD.

A small amount of electricity delivered at a specific frequency to a particular point in the brain will snap a monkey out of even deep anesthesia, pointing to a circuit of brain activity key to consciousness and suggesting potential treatments for debilitating brain disorders.

Macaques put under with general anesthetic drugs commonly administered to human surgical patients, propofol and isoflurane, could be revived and alert within two or three seconds of applying low current, according to a study published today in the journal Neuron by a team led by University of Wisconsin–Madison brain researchers.

“For as long as you’re stimulating their brain, their behavior — full eye opening, reaching for objects in their vicinity, vital sign changes, bodily movements and facial movements — and their brain activity is that of a waking state,” says Yuri Saalmann, UW–Madison psychology and neuroscience professor. “Then, within a few seconds of switching off the stimulation, their eyes closed again. The animal is right back into an unconscious state.”

A new study suggests a better way to match patients with depression to a medication.