Lifeboat Foundation

The hard, magnetic teeth of a leathery red-brown mollusk nicknamed “the wandering meatloaf” possess a rare mineral previously seen only in rocks. The mineral may help the mollusk — the giant Pacific chiton (Cryptochiton stelleri) — meld its soft flesh to the hard teeth it uses for grazing on rocky coastlines, researchers report online May 31 in Proceedings of the National Academy of Sciences.

C. stelleri is the world’s largest chiton, reaching up to roughly 35 centimeters long. It is equipped with several dozen rows of teeth on a slender, flexible, tonguelike appendage called a radula that it uses to scrape algae off rocks. Those teeth are covered in magnetite, the hardest, stiffest known biomineral to date: It’s as much as three times as hard as human enamel and mollusk shells.

Materials scientist Derk Joester and colleagues analyzed these teeth using high-energy X-rays from the Advanced Photon Source at Argonne National Laboratory in Lemont, Ill. They discovered that the interface between the teeth and flesh contained nanoparticles of santabarbaraite, an iron-loaded mineral never seen before in a living organism’s body.

Continue reading “The teeth of ‘wandering meatloaf’ contain a rare mineral found only in rocks” »

Check out this short educational video in which I explain some super exciting research in the area of nanotechnology: gigadalton-scale DNA origami! I specifically discuss a journal article by Wagenbauer et al. titled “Gigadalton-scale shape-programmable DNA assemblies”.

Here, I explain an exciting nanotechnology paper “Gigadalton-scale shape-programmable DNA assemblies” (https://doi.org/10.1038/nature24651).

Continue reading “Gigadalton-scale DNA origami nanostructures explained” »

New research in Nano Energy introduces revolutionary scalable material that senses and powers itself.

From the biggest bridges to the smallest medical implants, sensors are everywhere, and for good reason: The ability to sense and monitor changes before they become problems can be both cost-saving and life-saving.

To better address these potential threats, the Intelligent Structural Monitoring and Response Testing (iSMaRT) Lab at the University of Pittsburgh Swanson School of Engineering has designed a new class of materials that are both sensing mediums and nanogenerators, and are poised to revolutionize the multifunctional material technology big and small.

Continue reading “Revolutionary Self-Aware Materials Build the Foundation for Living Structures” »

A first-in-human, Phase 1 trial assessing the safety and immunogenicity of an investigational nanoparticle influenza vaccine designed to provide long-lasting protection against multiple flu virus strains has begun at the National Institutes of Health Clinical Center in Bethesda, Maryland. Healthy participants 18 to 50 years old will receive either a licensed seasonal influenza vaccine or the experimental vaccine, FluMos-v1. Scientists from NIH’s National Institute of Allergy and Infectious Diseases (NIAID) developed FluMos-v1 to stimulate antibodies against multiple influenza virus strains by displaying part of the influenza virus hemagglutinin (HA) protein on self-assembling nanoparticle scaffolds. Alicia T. Widge, M.D., of NIAID’s Vaccine Research Center (VRC), is the principal investigator of the NIAID-sponsored single-site trial.

“The health and economic burdens of influenza are substantial, and the world badly needs improved flu vaccines,” said NIAID Director Anthony S. Fauci, M.D. “I am encouraged by the great promise of the VRC nanoparticle vaccine candidate, which so far has performed very well in pre-clinical testing.”

Standard influenza vaccines must be reformulated and administered annually to match changes in the HA protein in the viral strains predicted to dominate in the upcoming influenza season. If the vaccine is not well matched to dominant circulating virus strains, the antibodies elicited may provide sub-optimal protection. So-called universal influenza vaccines are being developed and tested by many research groups and could one day eliminate the need for annual vaccination by generating long-lasting antibodies to protect against many existing or emergent influenza virus strains, including those not represented in the vaccine.

Continue reading “NIH launches clinical trial of universal influenza vaccine candidate” »

JÜLICH, Germany, May 28, 2021 — Quantum systems are considered extremely fragile. Even the smallest interactions with the environment can result in the loss of sensitive quantum effects. In the renowned journal Science, however, researchers from TU Delft, RWTH Aachen University and Forschungszentrum Jülich now present an experiment in which a quantum system consisting of two coupled atoms behaves surprisingly stable under electron bombardment. The experiment provide an indication that special quantum states might be realised in a quantum computer more easily than previously thought.

The so-called decoherence is one of the greatest enemies of the quantum physicist. Experts understand by this the decay of quantum states. This inevitably occurs when the system interacts with its environment. In the macroscopic world, this exchange is unavoidable, which is why quantum effects rarely occur in daily life. The quantum systems used in research, such as individual atoms, electrons or photons, are better shielded, but are fundamentally similarly sensitive.

“Systems subject to quantum physics, unlike classical objects, are not sharply defined in all their properties. Instead, they can occupy several states at once. This is called superposition,” Markus Ternes explains. “A famous example is Schrödinger’s thought experiment with the cat, which is temporarily dead and alive at the same time. However, the superposition breaks down as soon as the system is disturbed or measured. What is left then is only a single state, which is the measured value,” says the quantum physicist from Forschungszentrum Jülich and RWTH Aachen University.

Continue reading “Quantum Nanoscience Experiment in ‘Science’ Raises Questions” »

Scientists have taken a step towards the creation of powerful devices that harness magnetic charge by creating the first ever three-dimensional replica of a material known as a spin-ice.

Spin ice materials are extremely unusual as they possess so-called defects which behave as the single pole of a magnet.

These single pole magnets, also known as magnetic monopoles, do not exist in nature; when every magnetic material is cut into two it will always create a new magnet with a north and south pole.

Much of human invention and innovation has been the result of our discovery and replication of natural phenomena, from birds in flight to whales that dive deep into the ocean. For the first time, researchers have captured at the nanometer level the gliding machinery of the bacterium Mycoplasma mobile. Their findings were published in mBio. It illuminates the origin and operating principle of motility, which could serve as a basis for the next generation of nanoscale devices and pharmaceuticals.

“My lab has been studying the molecular nature of bacteria from the Mycoplasma genus for years,” states Professor Makoto Miyata from the Graduate School of Science, Osaka City University and lead of the research group. “And we have developed a conceptualization of how some of these parasitic bacteria ‘glide’ around their hosts.”

For example, Mycoplasma mobile forms a protrusion at one end giving the bacterium a flask shape. At the tapered end are external appendages that bind to solid surfaces, and in concert with an internal mechanism, cause the bacterium to glide across the surface of its host to find nutrient-rich sites and escape the host’s immune response.

More on thymus regeneration. Unless I understood wrong one patient’s epigenetic clock went from his mid 50’s to early 40’s.

Foresight Biotech & Health Extension Meeting sponsored by 100 Plus Capital.

Continue reading “Greg Fahy, Intervene Immune | Thymus Rejuvenation Progress Update” »

Scientists from Japan’s RIKEN Institute have developed a new ‘dry transfer technique’ which enables the precise positioning of optical-quality carbon nanotubes, without needing a solvent.