Lifeboat Foundation

The CellAge project hosted last year with Lifespan.io has now joined up with Michael Greve and Kizoo to develop this technology. Community support for the project has helped move the project foward and will hopefully speed up progress as a result.

April 2017, Edinburgh. CellAge Limited (“CellAge”) has raised a seed round backed by Michael Greve´s Kizoo Technology Capital and a group of angel investors.

CellAge, a privately held synthetic biology start-up aiming to develop tools and therapies for age-related diseases, has successfully completed a seed fundraising round. In this round Kizoo Technology Capital and a number of angel investors have joined the effort to develop synthetic promoters which will make senescent cells identification and removal safer and more efficient. To achieve this, CellAge is planning to analyze transcriptional profiles of a wide range of senescent cell types using proprietary algorithm and construct novel promoters from candidate regulatory elements identified in this screen. The joint expertise in senescence, synthetic biology and bioinformatics gives CellAge a unique angle on improving ways how gene therapies could be targeted to senescent cells.

AI vs aging the ultimate showdown is in the making.

There are several scientists that are now convinced upon the idea that while aging is a natural occurrence that happens in all creatures, it is, in fact, a disease that can be treated or cured. In that regards, there are some scientists out there looking to slow down the process of aging, while others are looking to stop it all together.

Continue reading “Could Artificial Intelligence Really Be Used to Attain Human Immortality?” »

A nice new write-up on my governor run: https://humanityplus.wordpress.com/2017/04/24/this-transhuma…alifornia/ #transhumanism

It’s a good time to be a transhumanist politician. As faith in the political establishment declines, new technologies, from gene editing to artificial intelligence, are transforming our lives faster than ever. The transhumanist author and politician Zoltan Istvan agrees. He thinks the time is ripe for pro-science and technology governance, and for leaders who will embrace the technologies that could fundamentally transform our conceptions of what it means to be human.

Istvan is a maverick who appears to thrive in an ‘outsider’ role. He self-published a sci-fi novel, The Transhumanist Wager, in 2013, which became a surprise bestseller on Amazon. In 2016, he made an unlikely run for US president as the leader of the Transhumanist Party. Now, he’s making a bid for Governor of California in the 2018 election under a Libertarian Party ticket.

Continue reading “This Transhumanist Politician Wants to be Governor of California” »

Fort Lauderdale, FL — Life Extension has partnered with Insilico Medicine to introduce Ageless Cell, the first supplement in its GEROPROTECT line to promote healthy aging by inhibiting cellular senescence.

Cellular senescence is a natural part of the aging process where cells no longer function optimally, affecting organ function, cellular metabolism, and inflammatory response. The accumulation of these senescent cells contributes to the process of aging. The Ageless Cell supplements inhibit the effects of cellular senescence by acting as geroprotectors, or interventions aimed to increase longevity and impede the onset of age-related diseases by targeting and inhibiting senescence-inducing pathways and inhibiting the development of senescent cells.

The partnership with Insilico Medicine allowed researchers to use deep learning algorithms to comb through hundreds of studies and thousands of data points — a process that could have taken decades — to identify four key anti-aging nutrients: N-Acetyl-L-Cysteine (NAC), myricetin, gamma-tocotrienol, and EGCG. These compounds target pathways that are known to contribute to or protect against the development of senescent cells.

Continue reading “Life Extension and Insilico Medicine Use AI to Develop Ageless Cell” »

https://www.youtube.com/watch?v=5TFHppPkvsM&feature=share

Over 2 million for one human treatment. Late 2017 trial on thumb sized primates.

This is perhaps the most significant medical breakthrough in human history. Dr. Bill Andrews explains the primate trial starting late 2017 and the first human treatments that are planned to fully lengthen human telomeres. While the treatment is expensive, the money will go towards finding a less expensive option so more people can afford the treatments. This is a segment cut from the full episode recorded March 22nd, 2017.

Continue reading “Cell Aging Solved, Full Telomere Lengthening Solution Trial late 2017- w/Dr. Bill Andrews” »

Elena Milova continues her coverage of the recent conference on aging in St-Peterberg.

During my recent journey to Saint-Petersburg to attend the in situ education program of the International Institute on Ageing of the United Nations, Malta (INIA), I asked one of the main speakers, former Head of the UN Programs on Ageing Dr. Alexandre Sidorenko, to find a few minutes to talk about his work.

Continue reading “From Vienna to Madrid and beyond: how the priorities of the United Nations relating to aging have changed over time” »

Elena Milova was our official LEAF Ambassador at a special education program organized by the International Institute on Ageing of the United Nations, Malta (INIA). We are all really proud of the hard work she has been doing for aging research.

Here is her discussion with Dr. Marvin Formosa — director of the INIA. Enjoy!

Continue reading “How population aging first became a matter of international concern” »

2017 begins on Monday in Vancouver, Canada, and will explore the theme “The Future You.” If the future you is anything like the future us, you are likely curled up in a big cushy chair right now, devouring the contents of a book that flips your thinking. Below, some reading suggestions from the speaker program. Read, enjoy and stay tuned to the TED Blog for beat-by-beat coverage of the conference.

TED2017 begins on Monday in Vancouver, Canada, and will explore the theme “The Future You.” If the future you is anything like the future us, you are likely curled up in a big cushy chair right now, devouring the contents of a book that flips your thinking. Below, some reading suggestions from the speaker program. Read, enjoy and stay tuned to the TED Blog for beat-by-beat coverage of the conference.

Weapons of Math Destruction: How Big Data Increases Inequality and Threatens Democracy by Cathy O’Neil. The decisions that affect our lives are no longer made by humans — they’re made by algorithms. This might sound like a great way around bias and discrimination, but these things are often built right into our mathematical models. When it comes to college admissions, decisions on parole, applications to jobs and the affects of a bad credit score, O’Neil explores the unintended consequences of algorithms. (Read an excerpt.)

Continue reading “15 books to browse ahead of TED2017” »

Some people fear rejuvenation therapies would be only for the privileged, and yet some others think they would be imposed on everyone. This article discusses the latter case.

Somebody once told me they fear that, if we created rejuvenation therapies, they might be forced on people who don’t want them, and in a way, we’d end up forcing people to live ‘forever’. Is this a good reason not to develop rejuvenation? No, of course not. I mean, imagine if we never came up with blood transfusions for fear that Jehovah’s witnesses might be forced to undergo them!

Besides, if rejuvenation therapies shouldn’t be invented because someone is afraid they’d be forced on people who want to grow old and die, let me ask: How about the people who do not want to grow old and die and yet would be forced to, because somebody else didn’t want rejuvenation therapies to be created? Dying despite the existence of rejuvenation therapies is certainly more easily attained than not dying despite the lack of rejuvenation therapies.

Rejuvenation is a set of medical interventions, and as such, a patient has the right to refuse all of them, if they want to. Indeed, the right to refuse or halt medical intervention already exists (see this WHO paper of 1994, page 11, article 3.2, which states this right for European Citizens, for example), so, if one really doesn’t want to undergo rejuvenation treatments, that is in their right already.

Continue reading “Rejuvenation would be forced on people” »