Cellular senescence is widely considered by academia to be one of the causes of aging and one that leads to a number of age-related diseases. There has been a high level of interest in recent years in cellular senescence and approaches that seek to remove senescent cells as a route to delaying or even preventing age-related diseases.
Today we have a new study where researchers focus on pulmonary fibrosis and the role of cellular senescence.
Transhumanists are curiosity addicts. If it’s new, different, untouched, or even despised, we’re probably interested in it. If it involves a revolution or a possible paradigm shift in human experience, you have our full attention. We are obsessed with the mysteries of existence, and we spend our time using the scientific method to explore anything we can find about the evolving universe and our tiny place in it.
Obsessive curiosity is a strange bedfellow. It stems from a profound sense of wanting something better in life—of not being satisfied. It makes one search, ponder, and strive for just about everything and anything that might improve existence. In the 21st century, that leads one right into transhumanism. That’s where I’ve landed right now: A journalist and activist in the transhumanist movement. I’m also currently a Libertarian candidate for California Governor. I advocate for science and tech-themed policies that give everyone the opportunity to live indefinitely in perfect health and freedom.
Politics aside, transhumanism is the international movement of using science and technology to radically change the human being and experience. Its primary goal is to deliver and embrace a utopian techno-optimistic world—a world that consists of biohackers, cyborgists, roboticists, life extension advocates, cryonicists, Singularitarians, and other science-devoted people.
“On August 3, sequencing company Veritas Genetics bought one of the most influential: seven-year old Curoverse. Veritas thinks AI will help interpret the genetic risk of certain diseases and scour the ever-growing databases of genomic, medical, and scientific research.”
As one of the most visible 2016 presidential candidates—and now as a leading 2018 contender for Governor in California—Zoltan Istvan has been the “Science Candidate,” traveling around America to discuss the issues of transhumanism and radical longevity that are transforming humanity. Soon the issues of AI, genetic editing, designer babies, bionic organs, automation, and neural prosthetics will challenge and dominate political discourse. America must embrace radical science with bold polices.
An interesting new study has demonstrated a method to reprogram specific T cells. Much like researchers have been experimenting recently with macrophages and making them change into an anti-inflammatory rather than a proinflammatory type, the team here has achieved similar results with T cells.
As we age the immune system becomes dysfunctional, either due to immune cells become overactive and creating too much inflammation or by cells that suppress the immune system such as senescent cells that inhibit cell function.
A dysfunctional immune system leaves us vulnerable to diseases and chronic levels of inflammation from excessive immune responses prevent tissue regeneration and wound healing. The researchers here have discovered how to target pro-inflammatory T cells that increase the immune response and inflammation and change them into anti-inflammatory cells that suppress the immune response, and vice versa.
Can we, as adults, grow new neurons? Neuroscientist Sandrine Thuret with a background in food science, molecular, cellular, behavioural and ageing biology says that we can, and she offers research and practical advice on how we can help our brains better perform neurogenesis—improving mood, increasing memory formation and preventing the decline associated with aging along the way.
“Can we, as adults, grow new nerve cells? There’s still some confusion about that question, as this is a fairly new field of research. For example, I was talking to one of my colleagues, Robert, who is an oncologist, and he was telling me, “Sandrine, this is puzzling. Some of my patients that have been told they are cured of their cancer still develop symptoms of depression.” And I responded to him, “Well, from my point of view that makes sense. The drug you give to your patients that stops the cancer cells multiplying also stops the newborn neurons being generated in their brain.” And then Robert looked at me like I was crazy and said, “But Sandrine, these are adult patients — adults do not grow new nerve cells.” And much to his surprise, I said, “Well actually, we do.” And this is a phenomenon that we call neurogenesis.”
