Lifeboat Foundation

J147 is an experimental drug that has been shown to treat Alzheimer’s disease, and it also appears to reverse some aspects of aging. It is also poised to enter human clinical trials in the near future, although how it works has been somewhat of a puzzle.

A new study published in the journal Aging Cell has changed all that, and the results are quite intriguing[1]. Researchers at the Salk Institute have solved the mystery of how J147 works and why it makes old flies, mice, and cells more youthful.

We have all heard that exercise is good for our health. However, it can not only keep you healthy, it can also slow down some aspects of aging. Some researchers even think that it might be possible to use this knowledge to develop new therapies against aging. While waiting for that to happen, we need to exercise in order to slow down the effects of aging.

How important is it to keep fit?

So, how beneficial is exercising? Well, one of the best studies conducted on this subject showed that women will live 5.6 years longer and men 6.2 years longer if they exercise between 1 and 2.5 hours per week[1]. This makes exercise a better lifestyle choice than any other, at least as long as you’re not counting avoiding downright dangerous behavior, such as smoking.

https://www.youtube.com/watch?v=dsJiZbLPqNQ

https://www.spreaker.com/user/xzoneradiotv/xzrs20180108epaemirapastor

AgeX, one of our supported startups aiming at turning basic research into actual rejuvenation therapies for human application, just published a breakthrough genetic discovery that could enable us to activate tissue regeneration capabilities in humans.

Dr. Mike West, CEO of AgeX, will also be presenting at undoing-aging.org

Continue reading “Discussion of iTR Publication” »

Today, we are going to take a look at a new study in which scientists at the Walter and Eliza Hall Institute of Medical Research have recently identified a type of cell that appears to be implied in thymic involution—the shrinking of the thymus[1].

Thymic involution is somewhat of a mystery in biology, a phenomenon that isn’t fully understood that happens to everyone with age and is a driving cause of immunosenescence, the age-related decline in our immune systems’ ability to fight disease. This new study helps to shed light on why it happens.

Dr. Oliver Medvedik Vice President of LEAF appears in this new TED interview where he talks about aging research and the possibilities of future medicine.

Aging happens to all of us, but scientists still don’t know the mechanism behind it. We need to focus on finding an answer, says molecular biologist Oliver Medvedik.

If given the option, would you choose to live forever? Many of us would say “yes,” but with one major caveat: just as long we don’t age. In scientific terms, aging means “a progressive loss of fitness in an organism over time,” says molecular biologist and TED Fellow Oliver Medvedik. What causes this loss of fitness in humans is multifaceted, although scientists are exploring different theories including — and these are just a few of the many avenues of research — the deterioration of the health of our telomeres (the ends of our chromosomes), changes in cell mitochondria, inefficient clearance of damaged cell proteins, and the senescence of stem cells, leading to chronic inflammation and a depletion of stem cells.

Continue reading “A crowdfunding platform aims to solve the puzzle of aging” »

New transhumanism story with many people in it. Forget the criticism in article, read what the highlighted people have said about the future. Great stuff.

A growing number of wealthy, tech-minded futurists are imagining life beyond their mortal bodies. We created images to match their strange, and varied, visions.