Lifeboat Foundation

Summary: A new study on aging reveals a surprising discovery about the connection between protein shape and mitochondrial health.

Source: Buck Institute.

Every cell in the body goes through thousands of chemical reactions each day, and each reaction involves tiny protein molecules folded into precise shapes to perform their functions. Misfolded proteins underlie some of the most common and devastating diseases of aging, like Alzheimer’s and Parkinson’s. A major focus of aging research is discovering ways to maintain protein shape and prevent misfolded proteins from wreaking havoc on cellular function.

Exploring The Gut Microbiota-Brain Axis In Health, Disease, and Aging — Dr. Marina Ezcurra, Ph.D. University of Kent.

Dr. Marina Ezcurra (https://marinaezcurralab.com/) is a Lecturer in the Biology of Aging, and NeuroBiology, at the School of BioSciences, at the University of Kent, UK (https://www.kent.ac.uk/biosciences/people/2081/ezcurra-marina).

Continue reading “Dr. Marina Ezcurra, Ph.D. — Exploring The Gut Microbiota-Brain Axis In Health, Disease, and Aging” »

Mentions telomeres.

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People with rare disorders that cause shortened telomeres—protective caps that sit at the end of chromosomes—may be more likely to have blood cancers such as leukemia or myelodyplastic syndrome. Now, Johns Hopkins Medicine scientists have discovered several “self-correcting” genetic mutations in bone marrow that may protect such patients from these cancers.

Continue reading “Gene self-correction in ‘chromosome caps’ can beat mutations, help prevent blood cancers” »

Summary: Researchers have identified 2,000 genes in humans linked to longevity. The genes are associated with biological mechanisms that drive the prolongation of life in mammals, including DNA repair, coagulation, and immune response.

Source: UPF Barcelona.

What determines the life expectancy of each species? This is a fundamental and highly complex question that has intrigued the field of research throughout history. From the evolutionary point of view, the major cause of these differences between species lies in their ecological adaptations. For example, life expectancy is longer in species adapted to living in trees, underground, or with large body mass, since all these adaptations reduce mortality by predation.

Youthereum talking about rejuvenation, funding, there is a history lesson here but the modern look starts at 38:01.

My overview of the history of partial reprogramming — a novel approach to epigenetic rejuvenation that uses short bursts of Yamanaka factors expression to periodically roll back the epigenetic state of cells to a younger pattern.

https://youtube.com/watch?v=8XUFrNQ7YSk

“After demonstrating that cultured meat can reach cost parity faster than the market anticipated, this production facility is the real game-changer,” said Yaakov Nahmias, Future Meat Technologies founder and chief scientific officer, in a press release. “This facility demonstrates our proprietary media rejuvenation technology in scale, allowing us to reach production densities 10-times higher than the industrial standard.”

Cultured meat is made by extracting cells from animal tissue and giving them nutrients, oxygen, and moisture while keeping them at the same temperature they’d be at inside an animal’s body. The cells divide and multiply then start to mature, with muscle cells joining to create muscle fibers and fat cells producing lipids. The resulting nuggets of meat can be used to make processed products like burgers or sausages. Structured cuts of meat with blood vessels and connective tissue, like steak or chicken breast, require scaffolds, and researchers are creating these with biomaterials, like cellulose from plants. Companies are working on several varieties of more elaborate cultured products, from bacon to salmon.

Continue reading “New Cultured Meat Factory Will Churn Out 5,000 Bioreactor Burgers a Day” »

Thanks Jeff

Jeff Bezos, the world richest man is investing in anti-ageing technology that could extend the average human lifespan by up to 50 years, WITHIN NIGERIA learnt.

It was also learnt that Jeff Bezos is one of the several billionaire investors in Altos Labs, a Silicon Valley tech firm working on experimental – and potentially dangerous – new life extension technologies.

Continue reading “Jeff Bezos funds anti-ageing technology to help humans ‘live forever’” »

Funders of a deep-pocketed new “rejuvenation” startup are said to include Jeff Bezos and Yuri Milner.

This is an excerpt I made from a conversation between Sergey Young and David Sinclair. Along it, they share their impressions as to how much Longevity science have progressed during the last few years.

The link to the entire conversation and the Q&As from the audience that was watching the webinar is in the description of the video.

Continue reading “David Sinclair on advances in the Longevity field during recent years (con S/T en Español)” »