Lifeboat Foundation

Within minutes of the final heartbeat, a cascade of biochemical events triggered by a lack of blood flow, oxygen, and nutrients begins to destroy a body’s cells and organs. But a team of Yale scientists has found that massive and permanent cellular failure doesn’t have to happen so quickly.

The researchers stressed that additional studies are necessary to understand the apparently restored motor functions in the animals, and that rigorous ethical review from other scientists and bioethicists is required.

The experimental protocols for the latest study were approved by Yale’s Institutional Animal Care and Use Committee and guided by an external advisory and ethics committee.

Continue reading “Yale-developed technology restores cell, organ function in pigs after death” »

A study into bone loss in astronauts returning from long spaceflights has shown that some may have incomplete bone recovery even after one year back on Earth, with sustained losses equivalent to 10 years of normal age-related bone loss on Earth.

An organism uses programmed cell death as a critical tool to maintain its health. Various stress responses are triggered when a cell does not operate as it should. These responses aim to bring back the original cell function.

One example is the process known as autophagy, in which a cell partly digests itself in order to acquire energy that it can utilize for its own repair. Should these efforts fail, the cell dies. This enables the body to combat conditions including infections, diabetes, cancer, and neurodegeneration.

Circa 2020 Reversing the biological clock to essentially reverse aging.

Expression of three Yamanaka transcription factors in mouse retinal ganglion cells restores youthful DNA methylation patterns, promotes axon regeneration after injury, and reverses vision loss in a mouse model of glaucoma and in aged mice, suggesting that mammalian tissues retain a record of youthfu…

Scientists at the University of Virginia School of Medicine and their collaborators have used DNA to overcome a nearly insurmountable obstacle to engineer materials that would revolutionize electronics.

Scientists around the world are scurrying to reverse the hands of time. Here’s a look at one lab’s search for the fountain of youth, where old mice have grown young again.

𝐖𝐡𝐚𝐭 𝐜𝐚𝐧 𝐬𝐞𝐚 𝐬𝐪𝐮𝐢𝐫𝐭𝐬 𝐭𝐞𝐥𝐥 𝐮𝐬 𝐚𝐛𝐨𝐮𝐭 𝐧𝐞𝐮𝐫𝐨𝐝𝐞𝐠𝐞𝐧𝐞𝐫𝐚𝐭𝐢𝐨𝐧?

A tiny marine creature with a strange lifestyle may provide valuable insights into human neurodegenerative disorders, such as Alzheimer’s disease, according to scientists at Stanford Medicine.

Botryllus schlosseri, also called a star tunicate, is humans’ closest evolutionary relative among invertebrates in the sea. Attached to rocks along the coast, it appears as a tiny flower-shaped organism. Star tunicates start life as little tadpole-like creatures with two brains, swimming in the ocean. But eventually they drift down from the surface, settling into a stationary life on a rock, joining a colony of other tunicates.

Continue reading “What can sea squirts tell us about neurodegeneration?” »

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Bristle Discount Link (Oral microbiome quantification):
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Continue reading “Blood Test #4 in 2022: Supplements, Diet” »

Summary: Study reveals how somatostatin and copper affect amyloid beta in Alzheimer’s disease pathology.

Source: KAIST

With nearly 50 million dementia patients worldwide, and Alzheimers’s disease is the most common neurodegenerative disease. Its main symptom is the impairment of general cognitive abilities, including the ability to speak or to remember.

Continue reading “How a Neurotransmitter May Be the Key in Controlling Alzheimer’s Toxicity​” »