Researchers developed a printing tech that doubles lithium-metal battery stability, making safer, high-capacity power for EVs.

There are currently over 750,000 patients with end-stage renal disease (ESRD) in the United States. Globally, 2.6 million patients receive renal replacement therapy with either dialysis or a kidney transplant, which is estimated to double in number by 2030. Kidney care was revolutionized by the invention of the dialysis machine in 1943 by Willem Kolff and the subsequent development of the arteriovenous fistula in 1960 by Belding Scribner. The first successful human kidney transplantation was performed in 1954 by Joseph Murray, teaming with John Merrill, and has since become the treatment of choice for patients with ESRD. Although there have been only incremental innovations since that time, recent exciting developments in kidney research have the potential to transform treatment beyond dialysis and transplantation. Here, we highlight five emerging approaches for ESRD.
(Circa 2022)
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A new study has revealed that autoantibodies—immune proteins traditionally associated with autoimmune disease—may profoundly influence how cancer patients respond to immunotherapy.
The study, published in Nature, offers a potential breakthrough in solving one of modern-day oncology’s most frustrating mysteries: why checkpoint inhibitors work for some patients but not others—and how we can extend their benefits to more people.
“Our analysis shows that certain naturally occurring autoantibodies can tilt the odds dramatically toward shrinking tumors,” said senior author Aaron Ring, MD, Ph.D., an associate professor at Fred Hutch Cancer Center. “We saw some cases where autoantibodies boosted a patient’s likelihood of responding to checkpoint blockade by as much as five-to ten-fold.”
In the battle against aggressive breast cancer, a once-elusive target is now within reach—thanks to a breakthrough from a team from the Faculty of Medicine at Hebrew University. Dr. Raphael Benhamou and M.Sc. student Liann Kassabri have developed innovative druglike molecules capable of degrading HuR, a key RNA-binding protein that stabilizes oncogenes and fuels cancer progression.
HuR (also known as ELAVL1) has long been labeled “undruggable” due to its structural flexibility and lack of a conventional active site. Overexpressed in many cancer types—particularly breast cancer—HuR fortifies malignant cells by protecting mRNAs that drive cell growth and survival.
“We knew that simply blocking HuR wasn’t enough,” says Dr. Benhamou. “We needed to eliminate it altogether.” Strikingly, this elimination led to a three to four orders of magnitude improvement in anticancer properties compared to traditional HuR-binding molecules that do not induce degradation.
A new study by Indiana University School of Medicine researchers has revealed a breakthrough in the fight against acute myeloid leukemia, one of the most aggressive and fatal blood cancers in adults. The discovery of a previously unrecognized immune cell could lead to new therapies that are less treatment-resistant than current options for patients—meaning higher survival rates for people with blood cancers.
Acute myeloid leukemia is a cancer that begins in the bone marrow and leads to impaired blood cell formation and function. Currently the sixth-leading cause of cancer-related death in adults, acute myeloid leukemia is resistant to many treatment options and relapse is common.
“Despite transformative progress in the treatment of many blood cancers, acute myeloid leukemia therapies have remained largely unchanged for over three decades,” said Reuben Kapur, Ph.D., director and program leader of the Hematologic Malignancies and Stem Cell Biology Program at the IU School of Medicine Herman B Wells Center for Pediatric Research, a researcher with the IU Melvin and Bren Simon Comprehensive Cancer Center and co-author of the study.
Stanford HAI offers critical resources for faculty and students to continue groundbreaking research across the vast AI landscape.
While roboticists have introduced increasingly advanced systems over the past decades, most existing robots are not yet able to manipulate objects with the same dexterity and sensing ability as humans. This, in turn, adversely impacts their performance in various real-world tasks, ranging from household chores to the clearing of rubble after natural disasters and the assembly or performing maintenance tasks, particularly in high-temperature working environments such as steel mills and foundries, where elevated temperatures can significantly degrade performance and compromise the precision required for safe operations.
Researchers at the University of Southern California recently developed the MOTIF (Multimodal Observation with Thermal, Inertial, and Force sensors) hand, a new robotic hand that could improve the object manipulation capabilities of humanoid robots. The innovation, presented in a paper posted to the arXiv preprint server, features a combination of sensing devices, including tactile sensors, a depth sensor, a thermal camera, inertial measurement unit (IMU) sensors and a visual sensor.
“Our paper emerged from the need to advance robotic manipulation beyond traditional visual and tactile sensing,” Daniel Seita, Hanyang Zhou, Wenhao Liu, and Haozhe Lou told Tech Xplore. “Current multi-fingered robotic hands often lack the integrated sensing capabilities necessary for complex tasks involving thermal awareness and responsive contact feedback.”