Hypothyroidism and hyperthyroidism are associated with gain and loss of body weight, respectively. This Review discusses the epidemiological evidence for weight changes in thyroid dysfunction, the role of thyroid hormone in weight regulation, the effect of treatment and the implications for population health.
In this video, Whitney, a registered dental hygienist, breaks down the viral headlines about a “tooth regrowth shot” being tested in Japan. She explains the real science behind the drug — how it targets the USAG-1 protein to potentially reactivate dormant tooth buds — and clears up common misconceptions about tooth regeneration research. From animal trials to current human safety studies, Whitney dives into what’s fact, what’s hype, and what this breakthrough could mean for the future of dentistry.
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https://bit.ly/4jgJPdG
• Born With Missing Teeth? (Hypodontia)
• What Happens If You Don’t Replace Your Mis…
• Regrowing vs Remineralizing Tooth Enamel.
▶ newsletter: https://bit.ly/ttg-subscribe.
▶ bettermouth app: https://www.bettermouth.com/
▶ website: https://teethtalkgirl.com.
▶ shop happyteeth: https://givehappyteeth.com/
▶ amazon storefront: https://www.amazon.com/shop/teethtalk?tag=lifeboatfound-20?tag=lifeboatfound-20.
▶ patreon: / teethtalkgirl.
▶ youtube: / @teethtalk.
Researchers in China report that global incidence rates of psoriasis rose slightly from 1990 to 2021 and are projected to continue rising for both men and women through 2050.
Psoriasis is a chronic inflammatory skin disease that continues to impose a growing global burden. Understanding the rate of increase is critical for informing public health strategies, improving health care access, and supporting early diagnosis worldwide.
In the study, “Global Psoriasis Burden and Forecasts to 2050,” published as a Research Letter in JAMA Dermatology, researchers used a time-series forecasting analysis to project global psoriasis incidence through 2050 and to address age, sex, and regional differences in burden.
This Commentary by Md Saidur Rahman, Kyeong A. So & Jae-Wook Jeong discusses Sylvia C. Hewitt et al.: https://doi.org/10.1172/JCI193212
1Department of Obstetrics, Gynecology & Women’s Health, University of Missouri School of Medicine, Columbia, Missouri, USA.
2Department of Obstetrics and Gynecology, Konkuk University School of Medicine, Seoul, Republic of Korea.
Address correspondence to: Jae-Wook Jeong, 1,030 Hitt Street, NextGen Precision Health Building, Columbia, Missouri 65,211, USA. Phone: 573.884.1882; Email: [email protected].
Researchers at UCLA have developed an artificial intelligence tool that can use electronic health records to identify patients with undiagnosed Alzheimer’s disease, addressing a critical gap in Alzheimer’s care: significant underdiagnosis, particularly among underrepresented communities.
The study appears in the journal npj Digital Medicine.
An interdisciplinary research team from Dresden University of Technology (TUD), Rostock University Medical Center (UMR) and Dresden University Hospital has developed an innovative, implantable and fully absorbable sensor film. For the first time, it enables reliable early detection of circulatory disorders in intestinal anastomoses—one of the riskiest surgical procedures in the abdominal cavity. The results have now been presented in the journal Advanced Science.
Intestinal anastomoses, which is the surgical connection of two sections of the intestine after the removal of diseased tissue, carry a considerable risk of post-operative complications. In particular, circulatory disorders or immunological reactions can lead to serious consequential damage or even death within a short period of time. However, direct monitoring of the suture site has not been possible until now, which often entails corresponding risks for patients as well as considerable costs due to follow-up operations and long hospital stays.
Based on this specific medical need, the interdisciplinary network of the Else Kröner Fresenius Center (EKFZ) for Digital Health at TUD and Dresden University Hospital brought together key experts from Dresden and Rostock.
Neal Agarwal published another gift to the internet with Size of Life. It shows the scale of living things, starting with DNA, to hemoglobin, and keeps going up.
The scientific illustrations are hand-drawn (without AI) by Julius Csotonyi. Sound & FX by Aleix Ramon and cello music by Iratxe Ibaibarriaga calm the mind and encourage a slow observation of things, but also grow in complexity and weight with the scale. It kind of feels like a meditation exercise.
See also: shrinking to an atom, the speed of light, and of course the classic Powers of Ten.
Photoplethysmography (PPG) is an optical sensing technique that measures blood volume changes and underpins devices ranging from hospital-grade pulse oximeters to consumer wearables that track heart rate, sleep, and oxygenation.
Despite its widespread use, PPG accuracy can vary significantly across individuals, particularly by skin tone. Darker skin contains more melanin, which absorbs and scatters light, often leading to less reliable readings. This disparity has been linked to inaccuracies in blood-oxygen measurements among people with more melanin.
Francesco J. DeMayo & team discover uterine ZMIZ1 co-regulates estrogen receptor to establish and maintain pregnancy and general uterine health via cell growth responses and preventing uterine fibrosis:
The figure shows epithelial cell DNA synthesis (reflected by EdU incorporation) was inhibited by Zmiz1 deletion.
1Pregnancy & Female Reproduction Group, Reproductive and Development al Biology Lab, NIEHS, Research Triangle Park, North Carolina, USA.
2Inotiv-RTP, Durham, North Carolina, USA.
3Division of Hematology-Oncology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, USA.