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Archive for the ‘genetics’ category: Page 76

Nov 11, 2023

Revolutionizing CRISPR: Quantum Biology and AI Merge to Enhance Genome Editing

Posted by in categories: bioengineering, biotech/medical, chemistry, genetics, quantum physics, robotics/AI

Oak Ridge National Laboratory’s research in quantum biology and AI has significantly improved the efficiency of CRISPR Cas9 genome editing in microbes, aiding in renewable energy development.

Scientists at Oak Ridge National Laboratory (ORNL) used their expertise in quantum biology, artificial intelligence, and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

CRISPR is a powerful tool for bioengineering, used to modify genetic code to improve an organism’s performance or to correct mutations. The CRISPR Cas9 tool relies on a single, unique guide RNA.

Nov 11, 2023

Scientists genetically engineer yeast to make safer schizophrenia drugs

Posted by in categories: biotech/medical, genetics, neuroscience

Treating mental disorders with fewer side effects

Now, researchers have managed to genetically modify yeast cells to produce drugs for mental disorders such as schizophrenia with fewer side effects.

“Development of medicines from natural plant substances is widely used. However, since plants do not produce these substances to fight human diseases, there is often a need to modify them to make them more effective and safe,” said Michael Krogh Jensen, a senior researcher at DTU Biosustain and co-founder of the biotech company Biomia.

Nov 11, 2023

5 ways to build an Alzheimer’s-resistant brain | Lisa Genova

Posted by in categories: biotech/medical, cybercrime/malcode, food, genetics, neuroscience

Only 2% of Alzheimer’s is 100% genetic. The rest is up to your daily habits.

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Nov 11, 2023

What If We Became A Type I Civilization? 15 Predictions

Posted by in categories: augmented reality, bioengineering, biological, genetics, Ray Kurzweil, robotics/AI, singularity, transhumanism

This video explores what life would be like if we became a Type I Civilization. Watch this next video about the Technological Singularity: https://youtu.be/yHEnKwSUzAE.
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Nov 10, 2023

Scientists Create Gene-Hacked Monkey That Glowed Green

Posted by in category: genetics

The lab-born primate, developed by Chinese scientists, made history as the world’s first live-born “chimeric” monkey. And: he glowed! Green!

Nov 10, 2023

In vivo ephaptic coupling allows memory network formation

Posted by in categories: genetics, mathematics, neuroscience

It is increasingly clear that memories are distributed across multiple brain areas. Such “engram complexes” are important features of memory formation and consolidation. Here, we test the hypothesis that engram complexes are formed in part by bioelectric fields that sculpt and guide the neural activity and tie together the areas that participate in engram complexes. Like the conductor of an orchestra, the fields influence each musician or neuron and orchestrate the output, the symphony. Our results use the theory of synergetics, machine learning, and data from a spatial delayed saccade task and provide evidence for in vivo ephaptic coupling in memory representations.

Nov 10, 2023

Rejuvenation Startup Summit 2024 Announces First Speakers

Posted by in categories: biotech/medical, genetics, life extension

The Rejuvenation Startup Summit (Berlin, May 10–11, 2024) hosted by the Forever Healthy Foundation, is a vibrant networking event that aims to accelerate the development of the rejuvenation biotech industry.

Rejuvenation/longevity biotech is a new, emerging field of medicine. It aims to prevent and reverse diseases of aging by addressing their common root cause, the aging process itself. Rejuvenation therapies aim to reverse or repair age-related cellular changes such as molecular waste, calcification, tissue stiffening, loss of stem cell function, genetic alterations, and impaired energy production.

Nov 9, 2023

The Kynurenine/Tryptophan Ratio: An Integrated Measure Of Many Pro- And Anti-Inflammatory Factors

Posted by in categories: biotech/medical, genetics, life extension

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Nov 9, 2023

Scientists use quantum biology, AI to sharpen genome editing tool

Posted by in categories: bioengineering, biotech/medical, chemistry, genetics, quantum physics, robotics/AI

Scientists at Oak Ridge National Laboratory have used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

CRISPR is a powerful tool for bioengineering, used to modify to improve an organism’s performance or to correct mutations. The CRISPR Cas9 tool relies on a single, unique guide RNA that directs the Cas9 enzyme to bind with and cleave the corresponding targeted site in the genome.

Existing models to computationally predict effective guide RNAs for CRISPR tools were built on data from only a few model species, with weak, inconsistent efficiency when applied to microbes.

Nov 8, 2023

Scientists engineer potent immune cells for ‘off-the-shelf’ cancer immunotherapy

Posted by in categories: biotech/medical, genetics, health

UCLA scientists have developed a new method to engineer more powerful immune cells that can potentially be used for “off-the-shelf” cell therapy to treat challenging cancers.

“Off-the-shelf” cell therapy, also known as allogenic therapy, uses derived from healthy donors instead of patients. The approach can bring , like (CAR) T cell therapy, to more patients in a timelier manner, which is one of the major barriers in getting these life-saving treatments to patients.

“Time is often of the essence when it comes to treating people with advanced cancers,” said Lili Yang, associate professor of microbiology, immunology and molecular genetics and member of the UCLA Health Jonsson Comprehensive Cancer Center. “Currently, these types of therapies need to be tailored to the individual patient. We have to extract from a patient, genetically engineer the cells and then re-infuse them back into the patient. This process can take weeks to months and can cost hundreds of thousands of dollars to treat each patient.”

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