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The scientists who developed the revolutionary gene-editing system known as CRISPR are improving it with new tools that make it work better.

A team of scientists have made a new discovery about naturally occurring magnetic materials, which in turn could lead to the development of nanoscale energy sources used to power next generation electronic devices. Researchers from Japan’s Okayama University and UC Riverside’s Bourns College of Engineering worked together to study the gumboot chiton, a type of mollusk that produces teeth made of the magnetic mineral magnetite, in hopes of better understanding its genetic process.

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Genetic testing could reveal mutation which make women more susceptible to breast and ovarian cancer. (Photo: iStockPhoto)

CRISPR And Human Embryo Experiments Underway In The U.S. : Shots — Health News Despite outrage over gene editing in China that affected the birth of twins, research is underway in the U.S. to assess the safety and effectiveness of CRISPR tools to edit genes in human embryos.

Dr. Rico explained: “When we compare human genomes from different people, we see that they are way more different than we initially expected when the Human Genome Project was declared to be ”completed” in 2003. One of the main contributions to these differences are the so called Copy Number Variable (CNV) regions. CNV regions are in different copy number depending on each individual, and their variability can be greater in some human populations than others. The number of copies of CNV regions can contribute to both normal phenotypic variability in the populations and susceptibility to certain diseases.

Research has shown a direct relationship between mutations in introns and variability in human populations.

One of the greatest challenges of genomics is to reveal what role the ”dark side” of the human genome plays: those regions where it has not yet been possible to find specific functions. The role that introns play within that immense part of the genome is especially mysterious. The introns, which represent almost half the size of the human genome, are constitutive parts of genes that alternate with regions that code for proteins, called exons.

Continue reading “Exploring the dark side of the genome” »

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Hosted by John Lewis of Oisin. Panel title: “A Therapeutic Revolution Against Aging”.

Aubrey de Grey, Judy Campisi, Nir Barzilai in a panel titled “A Therapeutic Revolution Against Aging”. Hosted by John Lewis of Oisin.

Continue reading “An amazing panel with Aubrey de Grey, Judy Campisi, and Nir Barzilai” »

A new aging clock developed by Professor Steve Horvath and his research team takes measuring your biological age a step further and can accurately predict your future lifespan.

The epigenetic clock

As we age, our DNA experiences chemical changes called DNA methylation (DNAm); these changes are used as a way to measure age and are the basis of the epigenetic clock. As we age, the methylation patterns present on our DNA change, and researchers can measure these changes to work out how old an animal or person is.

Continue reading “New Aging Clock Could Predict Your Future Lifespan” »

The assays don’t always yield results, but the information they offer can, at times, alter the course of treatment or prevention.

• By Jessica Wright, Spectrum on January 31, 2019