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A team of chemists at California Institute of Technology has totally synthesized perseanol using a 16-step process for the first time. In their paper published in the journal Nature, the group describes their process and how well it worked.

In nature, perseanol is a molecule produced by the persea tree. Shortly after its discovery in the late 1990s, researchers found that the molecule was similar to ryanodine, a once-popular pesticide. They have similar architecture, though perseanol lacks a pyrrole-2-carboxylate ester. Because of the similarities, interest in using perseanol on commercial crops grew. Not much later, a cheaper alternative was found, and the molecule never made it to the farm. But interest in it persists because of its ecofriendly reputation. For that reason, chemists have been working to produce it in the lab—if successful, the results would be both cheaper and more environmentally friendly than products now in use.

The researchers note that ryanodine works as a pesticide by binding to calcium channels in insects’ muscles, paralyzing them. It can paralyze animals, too, but perseanol is believed to be more specific to insects, making it a potentially safer pesticide. The researchers also note that little research has been performed to determine the means by which perseanol kills bugs. That could change however, if interest in using perseanol as a pesticide is rekindled.

A team including evolutionary biologists from the University of Toronto (U of T) have identified the ways in which herbicide-resistant strains of an invasive weed named common waterhemp have emerged in fields of soy and corn in southwestern Ontario.

They found that the resistance—which was first detected in Ontario in 2010—has spread thanks to two mechanisms: first, pollen and seeds of resistant plants are physically dispersed by wind, water and other means; second, resistance has appeared through the spontaneous emergence of resistance mutations that then spread.

The researchers found evidence of both mechanisms by comparing the genomes of herbicide-resistant waterhemp plants from Midwestern U.S. farms with the genomes of plants from Southern Ontario.

After three years of quietly toiling away on a robotic food system, Seattle startup Picnic has emerged from stealth mode with a system that assembles custom pizzas with little human intervention.

Picnic — previously known as Otto Robotics and Vivid Robotics — is the latest entrant in a cohort of startups and industry giants trying to find ways to automate restaurant kitchens in the face of slim margins and labor shortages. And its journey here wasn’t easy.

“Food is hard. It’s highly variable,” said Picnic CEO Clayton Wood. “We learned a lot about food science in the process of developing the system.”

When the structure of DNA was elucidated in 1953, an unimaginable world of possibilities was opened. But we couldn’t even begin to dream about how we would go about using such powerful knowledge. Thirty years later, PCR — the process to replicate DNA in the lab — was developed, and innovation exploded. In 2001 — nearly twenty years ago — the first full human genome was sequenced and published.

The information we’ve uncovered through DNA is enabling us to explore and develop solutions for a variety of problems, from how to mimic human disease in animal models to finding new treatments and cures for devastating diseases such as cancer and Alzheimer’s.

Continue reading “DNA spells tomorrow: how DNA tech will impact our world” »

Great Diet Information: #Longevity

Inflammation is also called the silent killer. It is silent because as your body struggles with inflammation, it also does all it can to maintain balance. This means that symptoms are sometimes hard to decipher and can even be hidden for some time.

Inflammation can be a good thing

Continue reading “Top 21 Anti Inflammatory Foods You Need To Add To Your Diet” »

“DNA is like a computer program but far, far more advanced than any software ever created.” Bill Gates wrote this in 1995, long before synthetic biology – a scientific discipline focused on reading, writing, and editing DNA – was being harnessed to program living cells. Today, the cost to order a custom DNA sequence has fallen faster than Moore’s law; perhaps that’s why the Microsoft founder is turning a significant part of his attention, and wallet, towards this exciting field.

Bill Gates is not the only tech founder billionaire that sees a parallel between bits and biology, either. Many other tech founders – the same people that made their money programming 1s and 0s – are now investing in biotech founders poised to make their own fortunes by programming A’s, T’s, G’s and C’s.

The industry has raised more than $12.3B in the last 10 years and last year, 98 synthetic biology companies collectively raised $3.8 billion, compared to just under $400 million total invested less than a decade ago. Synthetic biology companies are disrupting nearly every industry, from agriculture to medicine to cell-based meats. Engineered microorganisms are even being used to produce more sustainable fabrics and manufacture biofuels from recycled carbon emissions.

Imagine waking up every morning in a house that is just as alive as you are. With synthetic biology, your future home could be a living, breathing marvel of nature and biotechnology. Yes, it’s a bold ambition. But this kind of visionary thinking could be the key to achieving sustainability for modern cities.

Our current homes and cities are severely outdated. Dr. Rachel Armstrong, a synthetic biologist and experimental architect, says, “All our current buildings have something in common: they’re built using Victorian technologies.” Traditional design, manufacturing, and construction processes demand huge amounts of energy and resources, but the resulting buildings give nothing back. To make our future sustainable, we need dynamic structures that give as much as they take. We need to build with nature, not against it.

In nature, everything is connected. For the world’s tallest trees—the California redwoods— their lives depend on their connection to each other as well as on a host of symbiotic organisms. Winds and rain batter the California coast, so redwoods weave their roots together for stability, creating networks that can stretch hundreds of miles. The rains also leach nutrients from the soil. But fungi fill the shortage by breaking down dead organic matter into food for the living. A secondary network of mycelia—the root-like structures of the fungi—entwine with the tree roots to transport nutrients, water, and chemical communications throughout the forest. What if our future cities functioned like these symbiotic networks? What if our future homes were alive?

If you have more than one pet, then you know how chaotic feeding time can be. Italian company Volta is hoping to make the process just a little bit easier with its AI-driven pet feeder, Mookkie, which visually recognizes each individual cat or dog and places their prepared food at each pet’s disposal.

The Mookkie, winner of the Innovation Award in the Smart Home category at CES 2019, features a wide-angle camera that deploys logic similar to the “face-unlock” feature of smartphones.

Continue reading “This Pet Feeder Uses Facial Recognition So the Right Pet Gets the Treats” »

Giving a new meaning to fast food.

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