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This lecture was recorded on February 3, 2003 as part of the Distinguished Science Lecture Series hosted by Michael Shermer and presented by The Skeptics Society in California (1992–2015).

Can there be freedom and free will in a deterministic world? Renowned philosopher and public intellectual, Dr. Dennett, drawing on evolutionary biology, cognitive neuroscience, economics and philosophy, demonstrates that free will exists in a deterministic world for humans only, and that this gives us morality, meaning, and moral culpability. Weaving a richly detailed narrative, Dennett explains in a series of strikingly original arguments that far from being an enemy of traditional explorations of freedom, morality, and meaning, the evolutionary perspective can be an indispensable ally. In Freedom Evolves, Dennett seeks to place ethics on the foundation it deserves: a realistic, naturalistic, potentially unified vision of our place in nature.

Dr. Daniel Dennett — Freedom Evolves: Free Will, Determinism, and Evolution

Watch some of the past lectures for free online.

Where are all the aliens?! This is the essence to the Fermi Paradox. It’s most popular solution is the “Great Filter.” What is the obstacle that life and/or intelligent species are unlikely to survive? Let’s discuss.

00:00 Cold Open.
00:18 Introduction.
00:48 History of the Fermi Paradox.
02:48 Fermi Paradox Explained.
03:55 Drake Equation Explained.
07:04 The Great Filter.
09:56 Rare Earth Hypothesis.
10:53 Geologic Time in Galactic Years.
14:48 Evolution of Intelligent Life.
17:03 Conclusions.
19:11 Poll Results.
19:47 Outro.
20:10 Featured Comment.

Nick Lucid — Host/Writer/Editor/Animator.
Natalie Wells — Researcher.

VIDEO ANNOTATIONS/CARDS

Scientists have long pondered how and when the evolution of prokaryotes to eukaryotes occurred. A collaborative research team from Tohoku University and the University of Tokyo may have provided some answers after discovering new types of microfossils dating 1.9 billion years.

Details of their findings were published in the journal Precambrian Research on August 19, 2022.

The Gunflint Formation traverses the northern part of Minnesota into Ontario, along the northwestern shores of Lake Superior. The first bacterial microfossils were discovered there in 1954, with Gunflint microfossils now recognized as a “benchmark” in the field of life evolution.

The axolotl (Ambystoma mexicanum) is an aquatic salamander renowned for its ability to regenerate its spinal cord, heart and limbs. These amphibians also readily make new neurons throughout their lives. In 1964, researchers observed that adult axolotls could regenerate parts of their brains, even if a large section was completely removed. But one study found that axolotl brain regeneration has a limited ability to rebuild original tissue structure.

So how perfectly can ’s regenerate their brains after injury?

As a researcher studying regeneration at the cellular level, I and my colleagues in the Treutlein Lab at ETH Zurich and the Tanaka Lab at the Institute of Molecular Pathology in Vienna wondered whether axolotls are able to regenerate all the different in their brain, including the connections linking one brain region to another. In our recently published study, we created an atlas of the cells that make up a part of the axolotl brain, shedding light on both the way it regenerates and brain evolution across species.

Circa 2016 This gives more exacting detail of the Tasmanian devils resistance to cancer.


A recently emerged infectious cancer has caused the near extinction of the Tasmanian devil, but some populations persist. Here, Epstein et al. provide evidence for possible resistance via rapid evolution in two genomic regions that contain cancer-related immune response genes.

Evolution has long been thought to be random, however, a recent study suggests differently.

Evolution has long been thought of as a relatively random process, with species’ features being formed by random mutations and environmental factors and thus largely unpredictable.

But an international team of scientists headed by researchers from Yale University and Columbia University discovered that a specific plant lineage independently developed three similar leaf types repeatedly in mountainous places scattered across the Neotropics.

O.o!!!!!


Changing the number of chromosomes an animal has can take millions of generations to happen in nature through the course of evolution – and now, scientists have been able to make these same changes in lab mice in a relative blink of an eye.

The new technique using stem cells and gene editing is a major accomplishment, and one that the team is hoping will reveal more about how the rearrangement of chromosomes can influence the way that animals evolve over time.

It’s in chromosomes – those strings of protein and DNA inside cells – that we find our genes, inherited from our parents and blended together to make us who we are.

Analysis of the genome and proteome shows that eukaryotic evolution gave rise to the regulatory function of chromatin.

Two meters of DNA

DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).