Using CRISPR, Sandia National Lab researchers are genetically engineering antiviral countermeasures to fight the coronavirus—and potentially future outbreaks.
Writing in the journal NanoResearch, a team at the University of Massachusetts Amherst reports this week that they have developed bioelectronic ammonia gas sensors that are among the most sensitive ever made.
The sensor uses electric-charge-conducting protein nanowires derived from the bacterium Geobacter to provide biomaterials for electrical devices. More than 30 years ago, senior author and microbiologist Derek Lovley discovered Geobacter in river mud. The microbes grow hair-like protein filaments that work as nanoscale “wires” to transfer charges for their nourishment and to communicate with other bacteria.
First author and biomedical engineering doctoral student Alexander Smith, with his advisor Jun Yao and Lovley, say they designed this first sensor to measure ammonia because that gas is important to agriculture, the environment and biomedicine. For example, in humans, ammonia on the breath may signal disease, while in poultry farming, the gas must be closely monitored and controlled for bird health and comfort and to avoid feed imbalances and production losses.
A research team including Kanazawa University tests the impact response of the world’s hardest concrete.
Concrete is the most widely used building material in the world and consequently is being continuously developed to fulfill modern-day requirements. Efforts to improve concrete strength have led to reports of porosity-free concrete (PFC), the hardest concrete tested to date. Some of the basic properties of PFC have already been explored, and now a team including Kanazawa University has probed the impact response of this innovative material. Their findings are published in International Journal of Civil Engineering.
Ultra-high-strength concrete offers significant advantages including reducing the weight of large structures and protecting them against natural disasters and accidental impacts. PFC is an ultra-high-strength concrete whose properties can be further enhanced by incorporating steel fibers.
Stroke is the leading cause of serious long-term disability in the US with approximately 17 million individuals experiencing it each year. About 8 out of 10 stroke survivors suffer from “hemiparesis”, a paralysis that typically impacts the limbs and facial muscles on one side of their bodies, and often causes severe difficulties walking, a loss of balance with an increased risk of falling, as well as muscle fatigue that quickly sets in during exertions. Oftentimes, these impairments also make it impossible for them to perform basic everyday activities.
To allow stroke patients to recover, many rehabilitation centers have looked to robotic exoskeletons. But although there are now a range of exciting devices that are enabling people to walk again who initially were utterly unable to do so, there remains significant active research trying to understand how to best apply wearable robotics for rehabilitation after stroke. Despite the promise, recent clinical practice guidelines now even recommend against the use of robotic therapies when the goal is to improve walking speed or distance.
In 2017, a multidisciplinary team of mechanical and electrical engineers, apparel designers, and neurorehabilitation experts at Harvard’s Wyss Institute for Biologically Inspired Engineering and John A. Paulson School of Engineering and Applied Sciences (SEAS), and Boston University’s (BU) College of Health & Rehabilitation Sciences: Sargent College showed that an ankle-assisting soft robotic exosuit, tethered to an external battery and motor, was able to significantly improve biomechanical gait functions in stroke patients when worn while walking on a treadmill. The cross-institutional and cross-disciplinary team effort was led by Wyss faculty members Conor Walsh, Ph.D. and Lou Awad, P.T., D.P.T., Ph.D, together with Terry Ellis, Ph.D., P.T., N.C.S. from BU.
A new study from researchers at North Carolina State University suggests that a material consisting of a polymer compound embedded with bismuth trioxide particles holds tremendous potential for replacing conventional radiation shielding materials, such as lead.
The bismuth trioxide compound is lightweight, effective at shielding against ionizing radiation such as gamma rays, and can be manufactured quickly—making it a promising material for use in applications such as space exploration, medical imaging and radiation therapy.
“Traditional radiation shielding materials, like lead, are often expensive, heavy and toxic to human health and the environment,” says Ge Yang, an assistant professor of nuclear engineering at NC State and corresponding author of a paper on the work. “This proof-of-concept study shows that a bismuth trioxide compound could serve as effective radiation shielding, while mitigating the drawbacks associated with traditional shielding materials.”
Virtual #RegeneronISEF brings together the science and engineering community for a celebration of STEM in a free online event featuring top scientists and influential entrepreneurs. Register today!
The U.S. space agency National Aeronautics Space Administration (NASA), European Space Agency (ESA), and Japan Aerospace Exploration Agency (JAXA) are inviting coders, entrepreneurs, scientists, designers, storytellers, makers, builders, artists, and technologists to participate in a virtual hackathon May 30–31 dedicated to putting open data to work in developing solutions to issues related to the COVID-19 pandemic.
During the global Space Apps COVID-19 Challenge, participants from around the world will create virtual teams that – during a 48-hour period – will use Earth observation data to propose solutions to COVID-19-related challenges ranging from studying the coronavirus that causes COVID-19 and its spread to the impact the disease is having on the Earth system. Registration for this challenge opens in mid-May.
“There’s a tremendous need for our collective ingenuity right now,” said Thomas Zurbuchen, associate administrator for NASA’s Science Mission Directorate. “I can’t imagine a more worthy focus than COVID-19 on which to direct the energy and enthusiasm from around the world with the Space Apps Challenge that always generates such amazing solutions.”
The unique capabilities of NASA and its partner space agencies in the areas of science and technology enable them to lend a hand during this global crisis. Since the start of the global outbreak, Earth science specialists from each agency have been exploring ways to use unique Earth observation data to aid understanding of the interplay of the Earth system – on global to local scales – with aspects of the COVID-19 outbreak, including, potentially, our ability to combat it. The hackathon will also examine the human and economic response to the virus.
Continue reading “NASA, partners launch virtual hackathon to develop COVID-19 solutions” »
Circa 2019
The electrification of mobility has hit every industry to some degree or another, with some barely catching on but now doing so. The helicopter industry has been slow to adopt electricity, but the Californian consulting company Tier 1 Engineering is up to the challenge. Tier 1 Engineering Converts a Helicopter to Electricity, Snatches Guinness World Record
Inspired by the biomechanics of cheetahs, researchers have developed a new type of soft robot that is capable of moving more quickly on solid surfaces or in the water than previous generations of soft robots. The new soft robotics are also capable of grabbing objects delicately—or with sufficient strength to lift heavy objects.
“Cheetahs are the fastest creatures on land, and they derive their speed and power from the flexing of their spines,” says Jie Yin, an assistant professor of mechanical and aerospace engineering at North Carolina State University and corresponding author of a paper on the new soft robots.
“We were inspired by the cheetah to create a type of soft robot that has a spring-powered, ‘bistable’ spine, meaning that the robot has two stable states,” Yin says. “We can switch between these stable states rapidly by pumping air into channels that line the soft, silicone robot. Switching between the two states releases a significant amount of energy, allowing the robot to quickly exert force against the ground. This enables the robot to gallop across the surface, meaning that its feet leave the ground.
Researchers at Japan advanced institute of science and technology (JAIST) have successfully fabrication the suspended graphene nanomesh in a large area by the helium ion beam microscopy. 6nm diameter nanopores were pattern on the 1.2 um long and 500 nm wide suspended graphene uniformly. By systematically controlling the pitch (nanopore’s center to nanopore’s center) from 15 nm to 50 nm, a series of stable graphene nanomesh devices were achieved. This provides a practical way to investigate the intrinsic properties of graphene nanomesh towards the application for gas sensing, phonon engineering, and quantum technology.
Graphene, with its excellent electrical, thermal and optical properties, is promising for many applications in the next decade. It is also a potential candidate instead of silicon to build the next generation of electrical circuits. However, without a bandgap, it is not straightforward to use graphene as field-effect transistors (FETs). Researchers tried to cut the graphene sheet into a small piece of graphene nanoribbon and observed the bandgap opening successfully. However, the current of graphene nanoribbons is too low to drive the integrated circuit. In this case, the graphene nanomesh is pointed out by introducing periodical nanopores on the graphene, which is also considered as very small graphene nanoribbon array.
A research team led by Dr Fayong Liu and Professor Hiroshi MIZUTA has demonstrated in collaboration with researchers at the National Institute of Advanced Industrial Science and Technology (AIST) that large area suspended graphene nanomesh is quickly achievable by the helium ion beam microscopy with sub-10 nm nanopore diameter and well-controlled pitches. Comparing to slow speed TEM patterning, the helium ion beam milling technique overcomes the speed limitation, and meanwhile, provides a high imaging resolution. With the initial electrical measurements, it has found that the thermal activation energy of the graphene nanomesh increased exponentially by increasing the porosity of the graphene nanomesh. This immediately provides a new method for bandgap engineering beyond the conventional nanoribbon method. The team plans to continue exploring graphene nanomesh towards the application of phonon engineering.
