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Archive for the ‘biotech/medical’ category: Page 2725

Sep 1, 2009

Keeping genes out of terrorists’ hands

Posted by in categories: biological, biotech/medical, chemistry, counterterrorism, existential risks, policy

Nature News reports of a growing concern over different standards for DNA screening and biosecurity:

“A standards war is brewing in the gene-synthesis industry. At stake is the way that the industry screens orders for hazardous toxins and genes, such as pieces of deadly viruses and bacteria. Two competing groups of companies are now proposing different sets of screening standards, and the results could be crucial for global biosecurity.

“If you have a company that persists with a lower standard, you can drag the industry down to a lower level,” says lawyer Stephen Maurer of the University of California, Berkeley, who is studying how the industry is developing responsible practices. “Now we have a standards war that is a race to the bottom.”

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Jul 26, 2009

Bioethics and the End of Discussion

Posted by in categories: biotech/medical, ethics

Abstract:

President Obama disbanded the President’s Council on Bioethics after it questioned his policy on embryonic stem cell research. White House press officer Reid Cherlin said that this was because the Council favored discussion over developing a shared consensus. This column lists a number of problems with Obama’s decision, and with his position on the most controversial bioethical issue of our time.

Bioethics and the End of Discussion

In early June, President Obama disbanded the President’s Council on Bioethics. According to White House press officer Reid Cherlin, this was because the Council was designed by the Bush administration to be “a philosophically leaning advisory group” that favored discussion over developing a shared consensus. http://www.nytimes.com/2009/06/18/us/politics/18ethics.html?_r=2

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Jul 6, 2009

Unique opportunity to sponsor research investigating an infectious cause and potential treatment for Alzheimer’s disease

Posted by in categories: biological, biotech/medical, neuroscience

Unique opportunity to sponsor research investigating an infectious cause and potential treatment for Alzheimer’s disease



Alzheimer’s disease afflicts some 20 million people world-wide, over 5 million people of whom reside in the United States. It is currently the seventh-leading cause of death in the US. The number of people with the disease is predicted to increase by over 50% by 2030. The economic as well as emotional costs are huge, the costs being estimated as more than $148 billion each year (direct and indirect, for of all types of dementia, to Medicare, Medicaid and businesses).

The causes of Alzheimer’s disease are unknown, apart from the very small proportion with familial disease. We are investigating the involvement of infectious agents in the disease, with particular emphasis on the virus that causes oral herpes/cold sores/fever blisters. We discovered that most elderly humans harbour this virus in their brains and that in those (and only those) who possess a certain genetic factor, the virus confers a strong risk of developing Alzheimer’s disease. Also, we found that the virus is directly involved with the characteristic abnormalities seen in the brains of Alzheimer’s disease patients.

There are several treatment possibilities available to combat this virus and all would be suitable candidates as therapies in Alzheimer’s disease. However, much more research is needed before trials of these agents for Alzheimer’s disease in humans can begin.

In these financially difficult times many funding bodies have to prioritise projects based around long established hypotheses. Projects involving new avenues of investigation can receive very positive comments by scientific reviewers, yet are rarely funded, as they almost always appear risky compared with projects largely confirming or expanding existing ideas. Such conservative projects are almost guaranteed to produce useful data, though with modest impact. This situation can mean that research proposals with the potential to transform our understanding of a disease and offer new approaches to its treatment never reach the threshold for funding and are not implemented, even though the potential and quality of the science is acknowledged by reviewers and funding panel.

It appears that our work examining a viral cause for Alzheimer’s disease is in this category. Despite our publishing a large number of potentially very exciting papers on this topic, and despite our research projects being reviewed favourably by scientific referees, few funding panels are prepared to commit resources to fund our work, as by doing so they deny funding to other more straightforward, very low risk projects.

We are therefore actively seeking sponsorship for several projects of varying costs to investigate the interaction of virus and specific genetic factor, the pathways of viral damage in the brain, and the effects of antiviral agents. All the projects would provide significant evidence strengthening the case for trialling antiviral agents in Alzheimer’s disease.

Antiviral agents would inhibit a likely major cause of the disease in contrast to current treatments, which merely inhibit the symptoms.

If any Lifeboat member knows of a company or individual that would be interested in sponsoring some of our research on Alzheimer’s disease then please contact me for further details.

Ruth Itzhaki

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May 18, 2009

Top 6 Upcoming Health Events

Posted by in categories: biotech/medical, events, futurism

The air is buzzing. People are talking about health more than ever before, and it’s good news for patients. Technology is making it possible for patients to take an active role in “participatory medicine”, partnering with their doctors to decide on the best course of action for their health.

Over the next few months, these 6 events will bring together patients, researchers, doctors, and health enthusiasts. Discussions, partnerships, and innovations will emerge. Keep your eye on these, and attend if you can!

1. TEDMED — October 27–30, http://www.tedmed.com
The medical version of the legendary TED conferences. From the TEDMED site: “The fifth in a series created by Marc Hodosh and Richard Saul Wurman, TEDMED celebrates conversations that demonstrate the intersection and connections between all things medical and healthcare related: from personal health to public health, devices to design and Hollywood to the hospital.” This year’s speakers include Dean Kamen, Craig Venter, Sanjay Gupta and Goldie Hawn..

2. Transform — September 13–15, http://centerforinnovation.mayo.edu/transform
A collaborative symposium at The Mayo Clinic Center for Innovation. From the Transform site: “Transform brings together a dynamic group of speakers and participants from inside and outside the health care industry to explore the intersections between human experience, health care delivery and new business models. Join us to imagine and create innovative ways to deliver a better health care experience in a 21st century world.”

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May 17, 2009

Dr. Moreau outlawed in LA — Panel Votes to Outlaw Human-Animal Hybrids

Posted by in categories: biological, biotech/medical, human trajectories

U.S. News and World Report — May 12, 2009, by KEVIN McGILL

BATON ROUGE, La.—Combining human and animal cells to create what are sometimes called “human-animal hybrids” would be a crime in Louisiana, punishable by up to 10 years in prison, under legislation approved Tuesday by a state Senate panel.

Scientific researchers in some areas have tried to create human embryonic stem cells, which scientists say could be used to develop treatment for a variety of human ailments, by placing human DNA into animal cells. But such practices are controversial for a number of reasons.

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May 4, 2009

Forever Young

Posted by in categories: biological, biotech/medical, futurism, human trajectories, media & arts, space

(Crossposted on the blog of Starship Reckless)

Eleven years ago, Random House published my book To Seek Out New Life: The Biology of Star Trek. With the occasion of the premiere of the Star Trek reboot film and with my mind still bruised from the turgid awfulness of Battlestar Galactica, I decided to post the epilogue of my book, very lightly updated — as an antidote to blasé pseudo-sophistication and a reminder that Prometheus is humanity’s best embodiment. My major hope for the new film is that Uhura does more than answer phones and/or smooch Kirk.

Coda: The Infinite Frontier

star-trekA younger science than physics, biology is more linear and less exotic than its older sibling. Whereas physics is (mostly) elegant and symmetric, biology is lunging and ungainly, bound to the material and macroscopic. Its predictions are more specific, its theories less sweeping. And yet, in the end, the exploration of life is the frontier that matters the most. Life gives meaning to all elegant theories and contraptions, life is where the worlds of cosmology and ethics intersect.

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May 3, 2009

Swine Flu Update: are we entering an Age of Pandemics?

Posted by in categories: biological, biotech/medical, existential risks, futurism, geopolitics, nanotechnology, space, sustainability

May 2: Many U.S. emergency rooms and hospitals crammed with people… ”Walking well” flood hospitals… Clinics double their traffic in major cities … ER rooms turn away EMT cases. — CNN

Update May 4: Confirmed cases of H1N1 virus now at 985 in 20 countries (Mexico: 590, 25 deaths) — WHO. In U.S.: 245 confirmed U.S. cases in 35 states. — CDC.

“We might be entering an Age of Pandemics… a broad array of dangerous emerging 21st-century diseases, man-made or natural, brand-new or old, newly resistant to our current vaccines and antiviral drugs…. Martin Rees bet $1,000 that bioterror or bioerror would unleash a catastrophic event claiming one million lives in the next two decades…. Why? Less forest, more contact with animals… more meat eating (Africans last year consumed nearly 700 million wild animals… numbers of chickens raised for food in China have increased 1,000-fold over the past few decades)… farmers cut down jungle, creating deforested areas that once served as barriers to the zoonotic viruses…” — Larry Brilliant, Wall Street Journal


Apr 29, 2009

DIYbio.org

Posted by in categories: biological, biotech/medical, chemistry, education, engineering, ethics, human trajectories, open access, open source

About

DIYbio is an organization that aims to help make biology a worthwhile pursuit for citizen scientists, amateur biologists, and DIY biological engineers who value openness and safety. This will require mechanisms for amateurs to increase their knowledge and skills, access to a community of experts, the development of a code of ethics, responsible oversight, and leadership on issues that are unique to doing biology outside of traditional professional settings.

What is DIYbio in 4 minutes?

Get Involved

You can read about current events and developments in the DIYbio community by reading or subscribing to the blog.

Get in contact or get involved through discussions on our mailing list, or by attending or hosting a local DIYbio meetup.

The mailing list is the best way to find out what’s happening with DIYbio right now. There is also a low-traffic announce list.

Find out about our featured projects, including our plans for public wetlabs, global FlashLab experiments, and our innovation of next-gen lab equipment on the Projects page.

Mar 23, 2009

Detecting Disease by Tattoo

Posted by in categories: biotech/medical, nanotechnology

If you ever swore to yourself (or to another) that you’d never get a tattoo, you may just want to reconsider. You may within just a couple of years have a very good reason to get one made out of “nanoink”.

As recently reported on Discovery News, “nanoink” allows for monitoring blood glucose in real-time right under the skin. It does so by using a hydrophobic nanoparticle that changes colors as glucose levels rise and fall. The ink consists of a glucose-detecting molecule, a color changing dye and a molecule that mimics glucose. These three particles continuously swish around inside a 120-nm orb. When glucose is present, the glucose-detecting molecule attaches and glows yellow; if absent, the ink turns orange.

The use of this technology has the advantage over traditional glucose monitoring, of course, in that there is a one-time needle stick for placing the tattoo over the tens of thousands of sticks that a diabetic will need to have over a lifetime.

Another advantage of nanoink tattooing: they can be removed. At least one researcher from Brown University has developed tattoo ink with microencapsulated beads coated with a polymer that when broken with a single laser treatment can simply be expelled from the body, as opposed to multiple laser removal treatments for conventional tattoos.

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Mar 12, 2009

Crowdsourced Women’s Health Books Released by CureTogether

Posted by in categories: biological, biotech/medical, information science, open access, open source

Over 300 Women Share Experiences, Treatments for Painful, Common Chronic Conditions

CureTogether, a Health 2.0 Startup based in Silicon Valley, has released the first crowdsourced books on vulvodynia and endometriosis: two common, poorly understood conditions causing daily pain for millions of women. Assembled from the input of 190 and 137 women living with these respective conditions, “Vulvodynia Heroes” and “Endometriosis Heroes” are the product of an ongoing online research study at http://www.curetogether.com.

“Patients came together and decided what symptoms and treatments they wanted to track. They went on to diligently gather detailed, quantitative data on their bodies and experiences,” said Alexandra Carmichael, co-Founder of CureTogether. “The hope of this book is to spread awareness, reach out to people in pain who may not have heard of endometriosis, and increase interest and funding for future research.”

“These heroes are pioneers not just in investigating their own condition, but in developing self-cure practices that others can follow.”, said Gary Wolf, Contributing Editor of Wired and Blogger at The Quantified Self. “Many other women who are suffering will find this very helpful and inspiring,” said Elizabeth Rummer, MSPT at the Pelvic Health and Rehabilitation Center in San Francisco. A patient with endometriosis added, “This is great. I am just starting to really appreciate what awesome power CureTogether can have.”

Endometriosis is a painful chronic condition that affects 5–10% of women, and vulvodyna affects up to 16% of women at some point in their lives. They are two of the most active condition communities at CureTogether, with information about symptoms, treatments, and causes added by over 300 women. The books are available at http://www.curetogether.com/VHeroes and http://www.curetogether.com/EHeroes.

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