Lifeboat Foundation

While CRISPR, nanobots and head transplants are making headlines as medical breakthroughs, a number of new technologies are also making progress tackling some of the toughest age-old diseases still plaguing millions of people in the poorest parts of the world.

In low income countries, over 75% of the population dies before the age of 70 due to infectious diseases including HIV/AIDS, lung infections, tuberculosis, diarrheal diseases, malaria, and increasingly, cardiovascular diseases. Over a third of deaths in low income countries are among children under age 14 primarily due to pneumonia, diarrheal diseases, malaria and neonatal complications. In the developed world, those living in extreme poverty, such as homeless populations, also die on average at age 48.

Over the last year, artificial intelligence, robotics and biotechnology have all generated a number of new solutions that have the potential to dramatically reduce these problems.

Continue reading “Fighting Developing World Disease With AI, Robotics, and Biotech” »

Nice read.

At the beginning of the movie 50/50, Adam Lerner is diagnosed with neurofibrosarcoma, a cancer of the spine’s nerve tissue. Adam sits in his doctor’s office while the doctor rattles off the word several times, but Adam has no idea what it means, or if there’s anything wrong with him at all. Eventually, his doctor uses the word “cancer,” and Adam’s perspective goes blurry, the doctor’s voice drowned out by a high-pitched ringing.

Many people have had real experiences like this one. Cancer is still one of the scariest words you can hear in a diagnosis. And chances are, you know someone who has heard it—almost 40 percent of adults are diagnosed with some form of it during their lifetime. Every patient’s story is different, and they don’t all have a happy ending. But because of decades of research into how cancer works, patients diagnosed with cancer today have a much better chance of survival than ever before.

Continue reading “How The Meaning Of Cancer Has Changed” »

Gene expression is the process by which genetic information is used to produce proteins, which are essential for cells to function properly and fulfil their many purposes. It takes place in two distinctive steps: first the transcription, which takes place in the nucleus, then the translation, in the cytoplasm. Control of gene expression is vital for cells to produce the exact proteins that are needed at the right moment. Until now, gene transcription and translation into proteins were thought to be two independent processes. Today, microbiologists at the University of Geneva (UNIGE), Switzerland, and at the European Molecular Biology Laboratory in Heidelberg (Germany) provide additional evidence that these two processes are intrinsically related and show that a protein complex called Ccr4-Not plays a key role in gene expression by acting as a messenger between the nucleus and the cytoplasm. Published in Cell Reports, these results shed light on the very mechanisms governing gene expression, a process that controls the life and death of our cells.

Gene expression refers to the biochemical processes through which the information that is stored in our genes is read like an instruction book to produce proteins that will make our cells function properly. Until now, gene expression was thought to take place in two distinctive steps: first transcription, which takes place in the nucleus, then translation, in the cytoplasm. Today, research led by UNIGE and the European Molecular Biology Laboratory shows that transcription and translation are intrinsically related and continuously influence one another. To do so, a very efficient communication within the cell, between the nucleus and the cytoplasm, is essential. This dialogue is made possible by a protein complex called Ccr4-Not, which globally determines the cell translational capacity.

Gene expression: a two-way street

Martine Collart and her team from the UNIGE Faculty of Medicine discovered in 2014 that the Ccr4-Not complex enables the cytoplasm to provide information to the nucleus during translation. Today, they prove that it is a two way-street communication as the nucleus also communicates information to the cytoplasm at all stages of gene expression, thanks to Ccr4-Not. This complex acts as a messenger between the nucleus and the cytoplasm to ensure that both transcription and translation levels are well adapted. It is also able to enhance translation to compensate for transcriptional stress, thus ensuring that gene expression remains well-balanced.

Nice and interesting Gene Mutation Discovery.

A single defect in a gene that codes for a histone — a “spool” that wraps idle DNA — is linked to pediatric cancers in a study published in the journal Science.

“Unlike most cancers that require multiple hits, we found that this particular mutation can form a tumor all by itself,” says Peter W. Lewis, an assistant professor of biomolecular chemistry in the School of Medicine and Public Health at the University of Wisconsin-Madison.

Continue reading “Gene regulatory mutation linked to rare childhood cancer” »

I remember years ago when researchers identified that families with high rates for severe allergies also had high rates of cancer. Today, we talk about cancer and immunology as an intertwined dependency. Just means we’re still understanding cancer, genetic mutations, and the trigger/s in causing cancer among families and individual.

Scientists say the NLCR5 gene allows cancer cells to escape the immune system. A test for the biomarker may predict how long a cancer patient can survive.

Hope for HIV patients.

In 2014, a team of researchers in the Lewis Katz School of Medicine at Temple University became the first to successfully eliminate the HIV-1 virus from cultured human cells. Fewer than two years later, the team has made further strides in its research by eliminating the virus from the genome of human T-cells using the specialized gene editing system they designed.

In a new study published in Scientific Reports, the researchers show that the method can both effectively and safely eliminate the virus from the DNA of human cells grown in culture.

Continue reading “Scientists prove effectiveness of gene editing system in eliminating HIV from DNA of CD4+ T-cells” »

It’s absolutely insane to go ahead with the summer Olympics in light of this horrid mess. It’s unlikely to end us. but it could hurt us all, badly. No disease of this kind could ask for a better opportunity to spread around the world than that which the Olympics are about to give it. It’s insane.

Probably not, but pathogens that damage brains may earn a special place in cosmic hell.

By Caleb A. Scharf on May 11, 2016.

Continue reading “Is Zika How Humanity Ends?” »

When I look at technology and other things; my brain just dissolves all boundaries/ scope of the technology was originally defined for. For me, this is and has always been in my own DNA since I was a toddler. When I first looked at VR/ AR, my future state vision just exploded immediately where and how this technology could be used, how it could transform industries and daily lives, and other future technologies. So, I am glad to see folks apply AR and VR in so many ways that will prove valuable to users, companies, and consumers.

NVIDIA is working with various companies in different sectors such as automotive, manufacturing, and medical to bring AR benefits in their business. It is working with Audi, General Motors (GM), and Ford (F) to create a VR application where the consumer can design a car by changing its wheels, paint, or seat leather. NVIDIA is also working with European (IEV) furniture manufacturer IKEA to build a virtual reality application that allows the user to design their own rooms and homes.

Beautiful!!!!

The Wyss Institute at Harvard is creating miniaturised versions of human organs that could one day be used to test drugs as specific as the patients that take them.