Lifeboat Foundation

Crystals are defined by their repeating, symmetrical patterns and long-range order. Unlike amorphous materials, in which atoms are randomly packed together, the atoms in a crystal are arranged in a predictable way. Quasicrystals are an exotic exception to this rule. First discovered in 1982, their atoms pack together in an orderly fashion, but in a mosaic-like pattern that doesn’t repeat and can’t be predicted from a small sample.

Being able to map out the position of individual atoms within a quasicrystal is a prerequisite for achieving a complete understanding of their structure and aids in designing them for specific applications, but conventional microscopy techniques don’t have the resolution to accomplish such a task.

In an effort to address this challenge, researchers from the University of Pennsylvania and the University of Michigan have engineered a quasicrystal that is formed by self-assembling nanoparticles, which are an order of magnitude larger than the atoms that comprise traditional quasicrystals. Their larger size enabled the team to use a suite of microscopy and simulation techniques to deduce, for the first time, the full three-dimensional configuration of a spontaneously formed quasicrystal.

Tissue engineering makes further progress for repairing damaged joints.

Writing in The Lancet, Swiss doctors report that cartilage cells harvested from patients’ own noses have been used to successfully produce cartilage transplants for the treatment of the knees of 10 adults (aged 18–55 years) whose cartilage was damaged by injury. Two years after reconstruction, most recipients reported improvements in pain, knee function, and quality of life, as well as developing repair tissue that is similar in composition to native cartilage.

Despite this promising start, however, the effectiveness of the procedure needs to be rigorously assessed in larger randomised trials compared to conventional treatments and with longer follow up before any firm conclusions can be drawn about its use in routine clinical practice, say the authors.

Continue reading “The Lancet: Swiss doctors report success of using cells from the nose to repair damaged knee joints 2 years post operation” »

Combination therapy to kick cancer to the curb!

Harnessing the body’s own immune system to destroy tumors is a tantalizing prospect that has yet to realize its full potential. However, a new advance from MIT may bring this strategy, known as cancer immunotherapy, closer to becoming reality.

In the new study, the researchers used a combination of four different therapies to activate both of the immune system’s two branches, producing a coordinated attack that led to the complete disappearance of large, aggressive tumors in mice.

Continue reading “Fighting cancer with the power of immunity” »

Gene therapy in a box could reduce costs and save lives.

Gene therapy — the process of genetically altering cells to treat disease — is a highly promising process being studied as a way to cure devastating conditions like genetic disorders, HIV, and even cancer.

But despite the great need for medical advances in these areas, gene therapy can only be performed at a handful of high-tech clinics around the world and require highly trained staff, meaning that it may never be accessible to the millions of people whose lives it could save.

Continue reading “Newly-developed ‘gene therapy in a box’ could save millions of lives” »

Craig Venter’s New Enterprise: You

Scientist who jump-started the Human Genome Project works to integrate ‘personalized and preventive care into the practice of medicine.’

Virtual Reality started its fascinating take-over of healthcare for the greatest pleasure of patients and doctors alike. Here are five great examples of medical VR transforming patient lives and how doctors work.

Using cells from the cartilage in patients’ noses, Swiss doctors have successfully made patches to treat 10 adults whose knee cartilage was damaged by injury.

Two years after the transplants, most of the patients grew new cartilage in their knees and reported improvements in pain, knee function and quality of life.

“We have developed a new, promising approach to the treatment of articular cartilage injuries,” said lead researcher Ivan Martin, a professor of tissue engineering at the University of Basel. The articular cartilage is the tissue that covers and protects the ends of the knee bones, and injuries to it can lead to degenerative joint conditions like osteoarthritis.

Continue reading “Cartilage from nose is used to repair bum knees” »

Sergei lost his arm when his son was four years old.

His son is now an engineer, and he built this for his dad.

Brushing your teeth has never been so important.

It is conceived that specific combinations of periodontal bacteria are associated with risk for the various forms of periodontitis. We hypothesized that such specificity is also related to human cause-specific death rates. We tested this hypothesis in a representative sample of the US population followed for a mean duration of 11 years and found that two specific patterns of 21 serum antibodies against periodontal bacteria were significantly associated with increased all-cause and/or diabetes-related mortalities. These data suggested that specific combinations of periodontal bacteria, even without inducing clinically significant periodontitis, may have a significant impact on human cause-specific death rates. Our findings implied that increased disease and mortality risk could be transmittable via the transfer of oral microbiota, and that developing personalized strategies and maintaining healthy oral microbiota beyond protection against periodontitis would be important to manage the risk.