Lifeboat Foundation

Interesting study on brain receptors.

Researchers from UZH have discovered how the perception of meaning changes in the brain under the influence of LSD. The serotonin 2A receptors are responsible for altered perception. This finding will help develop new courses of pharmacotherapy for psychiatric disorders such as depression, addictions or phobias.

Humans perceive everyday things and experiences differently and attach different meaning to pieces of music, for instance. In the case of psychiatric disorders, this perception is often altered. For patients suffering from addictions, for instance, drug stimuli are more meaningful than for people without an addiction. Or patients with phobias perceive the things or situations that scare them with exaggerated significance compared to healthy people. A heightened negative perception of the self is also characteristic of depressive patients. Just how this so-called personal relevance develops in the brain and which neuropharmacological mechanisms are behind it, however, have remained unclear.

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TDP-43 Protien tied to Alzheimers according to a Mayo Clinic Study.

Since the time of Dr. Alois Alzheimer himself, two proteins (beta-amyloid (Aβ) and tau) have become tantamount to Alzheimer’s disease (AD). But a Mayo Clinic study challenges the perception that these are the only important proteins accounting for the clinical features of the devastating disease.

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My doctor needs one of these.

CAE Healthcare announced the release of CAE VimedixAR, an ultrasound training simulator integrated with the Microsoft HoloLens, the world’s first self-contained holographic computer. The announcment marks CAE Healthcare as the first company to bring a commercial Microsoft HoloLens application to the medical simulation market.

VimedixAR delivers an unprecedented simulation-based training experience, allowing learners to interact and move freely within a clinical training environment that is augmented with holograms. For the first time, students will be able to examine 3D anatomy inside the body of the Vimedix manikin. As learners practice scanning an animated heart, lungs or abdomen, they will observe in real-time how the ultrasound beam cuts through anatomy to generate a ultrasound image.

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I cannot wait. However, wish they would look at cancer treatment as one of the first trials.

SCIENCE

Medical Robotics: Microrobots Could Be The Answer To Future Medicine

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Allergic diseases are making one’s life more complicated and almost all treatment is only suppressing the symptoms. Fortunately, Stephen Miller of Northwestern University and Lonnie Shea of the University of Michigan can now mask allergen particles on their way into the body. This teaches the immune system not to attack the allergens in the future.

Their latest research published in the journal PNAS finally introduces a way to actually cure allergies altogether, instead of concealing symptoms with antihistamines such as Benadryl and Claritin…

Read the complete article:

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Knowing how or why genes are turned on and off during development, as well as understanding how they respond to environmental changes, will prove to be useful in our quest to find ways to prevent diseases. In addition, while the human initiator is responsible for regulating more than half of human genes, there are other sequences that control gene activity. This achievement could lead scientists to discover other sequence signals.

“The solution of the human Initiator code will enable us to explore new frontiers in gene regulation. In the future, it will be possible to use the code to identify other regulatory signals and, in this way, gain a more complete understanding of how human genes are turned on and off,” Kadonaga says.

Luv this. True Girl Power!

11-year-old Jordan Reeves, who last year made the world a bit jollier with her 3D printed, glitter-shooting prosthetic arm, has become a source of inspiration for many. The young and remarkably ambitious girl, who was born without most of her left arm (it stops just above the elbow), has been showing off her 3D printed glitter prosthetic all around the U.S. for the past several months, was presented with Disney’s Dream Big, Princess award, and was given a 3D printer courtesy of Autodesk and Dremel.

Not only is she receiving recognition, however, but Reeves has continued her steadfast work and is creating more 3D printed prosthetic accessories and assistive tools. Her latest project, for instance, is working on developing a device that combines a medical-grade prosthetic arm with 3D printed, changeable attachments. Though decidedly less sparkly than her first make, the hybrid prosthetic could allow for a variety of 3D printed attachments (like a hand or a pirate hook). Jordan is developing the 3D printed prosthesis with the help of her prosthetist and her Autodesk mentor Sam Hobish.

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How can we turn this into a small handheld device 3D printer so it is portable for doctors without boarders, EMS units, battlefiled surgeons, and eventually part of our own medicine kits for home some day. We can make it happen.

During phase I of AFIRM, WFIRM scientists designed, built and tested a printer designed to print skin cells onto burn wounds. The “ink” is actually different kinds of skin cells. A scanner is used to determine wound size and depth. Different kinds of skin cells are found at different depths. This data guides the printer as it applies layers of the correct type of cells to cover the wound. You only need a patch of skin one-tenth the size of the burn to grow enough skin cells for skin printing.

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Babies born prematurely don’t use their expectations about the world to shape their brains as babies born at full term do, important evidence that this neural process is important to development.

The findings offer clues to the mystery of why otherwise healthy babies born prematurely face higher risk of developmental delays as they grow, according to researchers at Princeton University, the University of Rochester Medical Center and the University of Rochester.