Lifeboat Foundation

Dr. Alexandra Stolzing and Dr. Aubrey de Grey discuss.

Jennifer Doudna reflects on what she sees as achievements and misuses of CRISPR genetic editing method.

• Using a drug already approved for clinical trials, researchers were able to reduce brain damage and boost the growth of new brain cells in mice suffering from strokes.
• The research offers new hope to those dealing with the aftermath of strokes, which are the fifth leading cause of death in the United States.

Researchers from the University of Manchester have developed a new treatment that could limit the damage caused by strokes and also promote repair in the affected area of the brain. What’s more, the drug they’re using has already been clinically approved.

But a British PhD candidate has warned of the darker side of a transhumanist future.

Sociologist Alex Thomas of East London University believes that transhumanism will further enforce a societal obsession with “progress” and “efficiency” at the expense of social justice and environmental sustainability. In an article published this week in The Conversation, Thomas argues that unbridled technological progress, in which technology “become more intrusive and integrate seamlessly with the human body”, could lead to a loss of basic societal values such as compassion and a concern for the environment.

Transhumanism and advanced capitalism are two processes which value “progress” and “efficiency” above everything else. The former as a means to power and the latter as a means to profit. Humans become vessels to serve these values. Transhuman possibilities urgently call for a politics with more clearly delineated and explicit humane values to provide a safer environment in which to foster these profound changes.”

Continue reading “The risk of a transhumanist future” »

Cyborgs have arrived and are living among us. From pacemakers to bionic eyes to cochlear implants, these are all examples of biohacking.

An interesting new study has demonstrated a method to reprogram specific T cells. Much like researchers have been experimenting recently with macrophages and making them change into an anti-inflammatory rather than a proinflammatory type, the team here has achieved similar results with T cells.

As we age the immune system becomes dysfunctional, either due to immune cells become overactive and creating too much inflammation or by cells that suppress the immune system such as senescent cells that inhibit cell function.

A dysfunctional immune system leaves us vulnerable to diseases and chronic levels of inflammation from excessive immune responses prevent tissue regeneration and wound healing. The researchers here have discovered how to target pro-inflammatory T cells that increase the immune response and inflammation and change them into anti-inflammatory cells that suppress the immune response, and vice versa.

Obesity affects more than 600 million adults and around 41 million children under the age of 5 according to the Center for Disease Control and Prevention. Researchers may have found a way to halt the development of both type 2 diabetes and obesity in humans using a recently discovered protein.

In step forward for Elon Musk’s neural lace and transhumanists everywhere, a new paper published this month by researchers at Harvard University reports on the successful implantation of an electronic neuromorphic mesh in the brains of mice without triggering an immune response.

Neuroprostheses show promise in the treatment of Alzheimer’s Disease, Parkinson’s Disease, epilepsy, traumatic brain injury and for the creation of brain-machine interfaces such as the neural lace, but a major stumbling block for researchers has been the propensity of these implants to induce an immune response, inflammation and scaring in the brain, severely limiting their potential use.

Continue reading “Study Shows Injectable Electronic Neural Lace Melds With Neurons Without Causing Immune Response” »

Ready and waiting at an arms reach from the government, the Research and Development Corporation (RAND) has helped the U.S. think through some of the toughest scientific and regulatory challenges since the 1940s. This year, the think tank is opening its first office in the San Francisco Bay Area. Its positioning itself to weigh in on some of Silicon Valleys largest research projects, like autonomous vehicles, drones, AI, cybersecurity and telemedicine.

But unlike the RAND of the past, this new version embodies the scrappiness of startup culture. Formally based out of a WeWork space, office director Nidhi Kalra and the rest of her SF team largely work decentralized from homes and coffee shops around the Bay Area.

The team of a dozen researchers is here to study the development of new technologies and the way in which state and local authorities are working side-by-side with startups to keep everyone safe without sundering innovation.

Continue reading “The Wizards of Armageddon set up shop in Silicon Valley” »