Lifeboat Foundation

In the iconic frontispiece to Thomas Henry Huxley’s Evidence as to Man’s Place in Nature (1863), primate skeletons march across the page and, presumably, into the future: “Gibbon, Orang, Chimpanzee, Gorilla, Man.” Fresh evidence from anatomy and palaeontology had made humans’ place on the scala naturae scientifically irrefutable. We were unequivocally with the animals — albeit at the head of the line.

Biological advances have repeatedly changed who we think we are, writes Nathaniel Comfort, in the third essay of a series marking Nature’s anniversary on how the past 150 years have shaped science today. Biological advances have repeatedly changed who we think we are.

Researchers long wondered how the billions of independent neurons in the brain come together to reliably build a biological machine that easily beats the most advanced computers. All of those tiny interactions appear to be tied to something that guarantees an impressive computational capacity.

Over the past 20 years, evidence mounted in support of a theory that the brain tunes itself to a point where it is as excitable as it can be without tipping into disorder, similar to a phase transition. This criticality hypothesis asserts that the brain is poised on the fine line between quiescence and chaos. At exactly this line, information processing is maximized.

However, one of the key predictions of this theory—that criticality is truly a set point, and not a mere inevitability—had never been tested. Until now. New research from Washington University in St. Louis directly confirms this long-standing prediction in the brains of freely behaving animals.

EVANSTON, Ill. — A new Northwestern University study finds that despite human’s close genetic relationship to apes, the human gut microbiome is more similar to that of Old World monkeys like baboons than to that of apes like chimpanzees.

These results suggest that human ecology has had a stronger impact in shaping the human gut microbiome than genetic relationships. The results also suggest the human gut microbiome may have unique characteristics compared to other primates, including increased flexibility.

“Understanding what factors shaped the human gut microbiome over evolutionary time can help us understand how gut microbes may have influenced adaptation and evolution in our ancestors and how they interact with our biology and health today,” said Katherine Amato, lead author of the study and assistant professor of anthropology in the Weinberg College of Arts and Sciences at Northwestern.

To create sustainable cities, we need to use synthetic biology.

China has broken new lunar ground, successfully growing cotton on the moon for the first time. The experiment was part of the Chang’e 4 project, in which China is exploring the far side of the moon with a lander. This is the same lander that recently discovered a mysterious gel-like substance on the moon’s surface.

The cotton plant was one of several organisms encased in a mini biosphere weighing just 2.6 kilograms (5.7 lbs) with a pressure of 1 atmosphere which was aboard the lander. The organisms experienced an environment largely similar to that on Earth, however, they did have to contend with both space radiation and microgravity.

In an interview with engineering magazine IEEE Spectrum, project leader for the experiment Xie Gengxin explained more about the challenges of growing plants in the restricted environment. “The weight of the Chang’e-4 probe demanded that the weight [of the experiment] can’t exceed three kilograms,” he said. That’s why it was important to select the biological samples in the experiment carefully.

Download the podcast via Apple Podcasts, Google Play or Spotify.

Sandra Rey, 29, was participating in a student design competition with the theme “biology” and got to watching videos on YouTube of bioluminescent sea creatures when she thought there must be a way to replicate that natural technology. Five years later, her startup, called Glowee, is creating brilliant luminescent art installations for hotels and public spaces.

While she admits, “We’ll never replace the lights in your kitchen,” she hopes to create enough light and enough beauty to play a role in the world’s lighting mix to help reduce reliance on electric lighting.

For the “big data” revolution to continue, we need to radically rethink our hard drives. Thanks to evolution, we already have a clue.

Our bodies are jam-packed with data, tightly compacted inside microscopic structures within every cell. Take DNA: with just four letters we’re able to generate every single molecular process that keeps us running. That sort of combinatorial complexity is still unheard of in silicon-based data storage in computer chips.

Add this to the fact that DNA can be dehydrated and kept intact for eons—500,000 years and counting—and it’s no surprise that scientists have been exploiting its properties to encode information. To famed synthetic biologist Dr. George Church, looking to biology is a no-brainer: even the simple bacteria E. Coli has a data storage density of 10¹⁹ bits per cubic centimeter. Translation? Just a single cube of DNA measuring one meter each side can meet all of the world’s current data storage needs.

At SynBioBeta, entrepreneurs making plant-based foods and genetically engineered bacteria rallied to promote the idea that it’s biology’s century.

The idea that humans should merge with AI is very much in the air these days. It is offered both as a way for humans to avoid being outmoded by AI in the workplace, and as a path to superintelligence and immortality. For instance, Elon Musk recently commented that humans can escape being outmoded by AI by “having some sort of merger of biological intelligence and machine intelligence.”¹ To this end, he’s founded a company, Neuralink. One of its first aims is to develop “neural lace,” an injectable mesh that connects the brain directly to computers. Neural lace and other AI-based enhancements are supposed to allow data from your brain to travel wirelessly to one’s digital devices or to the cloud, where massive computing power is available.

For many transhumanists, uploading is key to the mind-machine merger.

Perhaps these sorts of enhancements will turn out to be beneficial, but to see if this is the case, we will need to move beyond all the hype. Policymakers, the public, and even AI researchers themselves need a better idea of what is at stake. For instance, if AI cannot be conscious, then if you substituted a microchip for the parts of the brain responsible for consciousness, you would end your life as a conscious being. You’d become what philosophers call a “zombie”—a nonconscious simulacrum of your earlier self. Further, even ifmicrochips could replace parts of the brain responsible for consciousness without zombifying you, radical enhancement is still a major risk. After too many changes, the person who remains may not even be you. Each human who enhances may, unbeknownst to them, end their life in the process.