Lifeboat Foundation

Researchers genetically modify piglets to be resistant to an incurable disease plaguing hog farms, Porcine Reproductive Respiratory Syndrome (PRSS). The researchers cut out a specific gene to cure the pigs.

A team of researchers from MIT have developed a new technique on the genome-editing system known as CRISPR, which offers precise manipulation of when and where gene editing occurs.

It’s an add-on for CRISPR.

Researchers have created a new genome editing technique called Target-AID, which induces point mutations instead of cutting DNA

Gene editing technology has fantastic potential, but there are remaining issues and questions over safety and specificity. The major contender is currently CRISPR-Cas9, but this induces a double stranded break in DNA which is a slightly riskier approach — particularly if it cuts in other locations too that you don’t want it to. Research teams across the world are both optimising and customising the CRISPR system; creating more accurate versions or versions that regulate gene expression as opposed to editing it. One such team has now built an add-on to CRISPR, Target-AID.

Continue reading “Safer Gene Editing Without Cleaving DNA” »

From selective breeding to genetic modification, our understanding of biology is now merging with the principles of engineering to bring us synthetic biology.

Written, animated and directed by James Hutson, Bridge8.

Continue reading “Synthetic Biology Explained” »

BrainGate technology is no longer the stuff of science fiction. The science of interfacing human brains and other biological neurons with computers has been developing for well over a decade and now, the progress is amazing. While the human mind is an amazing organ, that surpasses any computer ever made. Many fantasize about improving on natural skills and abilities using technology in the form of some sort of brain implant. That dream is about to become a reality. In some ways, it already has according to the BrainGate website.

“BrainGate Company’s current and planned intellectual property (the technology) is based on technology that can sense, transmit, analyze and apply the language of neurons. BrainGate consists of a sensor that is implanted on the motor cortex of the brain and a device that analyzes brain signals.”

Continue reading “The Cyborgs Are Coming: Mankind Is On The Cusp Of Human Brain Augmentation With BrainGate Technology” »

“Liquid Metals to “Soft-Wire” Elastic Electronics”

A few years ago, some friends shared with me an amazing experiment of theirs involving liquid/ fluid base circuitry. Definitely is amazing; and is going to be amazing in where we are taking this type of technology along with synthetic biology.

The shape-shifting metals behind the T-1000 android assassin in the sci-fi movie Terminator 2 may not remain science fiction for long with the development of self-propelling liquid metals that could lead to the replacement of solid state circuits by elastic electronics.

Continue reading “Liquid Metals to ‘Soft-Wire’ Elastic Electronics” »

#CRISPR can be used to alter the genes of not only one organism, but an entire species, through a method of inheritance known as a gene drive. But what happens if something goes awry?

More insights on human conscientious in relation to its state after we die.

Personally, (this is only my own opinion) I believe much of the human conscientious will remain a mystery even in the living as it relates to the re-creation of the human brain and its thinking and decision making patterns on current technology. Namely because any doctor will tell you that a person’s own decisions (namely emotional decision making/ thinking) can be impacted by a whole multitude of factors beyond logical information such as the brain’s chemical balance, physical illness or even injury, etc. which inherently feeds into conscientious state. In order to try to replicate this model means predominantly development of a machine that is predominantly built with synthetic biology; and even then we will need to evolve this model to finally understand human conscientious more than we do today.

Continue reading “World’s Scientists: ‘Human Consciousness Will Remain a Mystery’” »

Major advancement in Gene Editing.

A team involving Kobe University researchers has succeeded in developing ‘Target-AID’, a genome editing technique that does not cleave the DNA. The technique offers, through high-level editing operation, a method to address the existing issues of genome editing. It is expected that the technique will be applied to gene therapy in the future in addition to providing a powerful tool for breeding useful organisms and conducting disease and drug-discovery research. The findings were published online in Science on August 5.

The team consists of Project Associate Professor NISHIDA Keiji and Professor KONDO Akihiko (Graduate School of Science, Technology and Innovation, Kobe University) as well as Associate Professor YACHIE Nozomu (Synthetic Biology Division, Research Center for Advanced Science and Technology, the University of Tokyo) and Professor HARA Kiyotaka (Department of Environmental Sciences, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka).

Continue reading “Researchers succeed in developing a genome editing technique that does not cleave DNA” »