Scientists have taken a significant step towards the development of tailor-made chiral nanocarriers with controllable release properties. These nanocarriers, inspired by nature’s helical molecules like DNA and proteins, hold immense potential for targeted drug delivery and other biomedical applications.
Scientists have taken a significant step towards the development of tailor-made chiral nanocarriers with controllable release properties. These nanocarriers, inspired by nature’s helical molecules like DNA and proteins, hold immense potential for targeted drug delivery and other biomedical applications.The study, led by Professors Emilio Quiñoá and Félix Freire at the Center for Research in Biological Chemistry and Molecular Materials (CiQUS), highlights the intricate relationship between the structure of helical polymers and their self-assembly into nanospheres. By carefully designing the secondary chain, the researchers were able to modulate the acidity of the polymers, influencing their aggregation patterns and leading to the formation of nanoespheres with varying densities.
Intriguingly, the size of these nanospheres could be precisely controlled by simply adjusting the water-to-solvent ratio during their preparation, eliminating the need for stabilizers. This eco-friendly approach paves the way for sustainable synthesis of these particles.
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