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May 5, 2024

From Theory to Therapy: MIT’s Computational Breakthrough in Protein Optimization

Posted by in categories: computing, neuroscience

MIT researchers have developed a computational approach that makes it easier to predict mutations that will lead to optimized proteins, based on a relatively small amount of data. Credit: MIT News; iStock.

MIT researchers plan to search for proteins that could be used to measure electrical activity in the brain.

To engineer proteins with useful functions, researchers usually begin with a natural protein that has a desirable function, such as emitting fluorescent light, and put it through many rounds of random mutation that eventually generate an optimized version of the protein.

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