Denmark: A recent study published in JAMA Network Open has suggested an association between tooth agenesis and specific cancer types, specifically in childhood and early adulthood.
“Our population-based cohort study of 2.5 million live-born singletons with up to 40 years of follow-up showed that tooth agenesis was positively associated with several cancer types, including nephroblastoma, neuroblastoma, and hepatoblastoma in childhood; osteosarcoma in adolescence; and carcinomas of the bladder and colorectal carcinomas in young adulthood,” the researchers reported.
Previous studies have provided some evidence that tooth agenesis (congenital absence of one or more teeth) is associated with cancer risk, particularly carcinomas of the ovaries and colon, but these results are conflicting, and associations have not been evaluated yet in a population-based setting. To fill this knowledge gap, Saga Elise Eiset, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark, and colleagues aimed to investigate the association between tooth agenesis and specific cancer types before 40 years of age.
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