A Whole New World

Scientists have already found hundreds of exotic amino acids. AI models such as AlphaFold or RoseTTAFold, and their variations, are likely to spawn even more. Finding carriers and “glue” proteins that match has always been a roadblock.

The new study establishes a method to speed up the search for new designer proteins with unusual properties. For now, the method can only incorporate four synthetic amino acids. But scientists are already envisioning uses for them.