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A recent study published in the journal Npj Parkinson’s Disease investigated whether increased thinning rate in the parafoveal ganglion cell-inner plexiform layer (pfGCIPL) and peripapillary retinal nerve fiber layer (pRNFL) indicates the progression of the Parkinson’s disease (PD).
Study: Association of retinal neurodegeneration with the progression of cognitive decline in Parkinson’s disease. Image Credit: BioFoto / Shutterstock
Background
Retinal changes are robustly associated with neurodegenerative diseases, such as PD. The changes in retinal layer thickness can be assessed using high-resolution optical coherence tomography (OCT). Among different retinal layers, the ganglion cell-inner plexiform layer (GCIPL) can be used as a biomarker to determine cognitive decline and neurodegeneration.
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