An amazing graph theoretic analysis of the C. elegans neuropeptide connectome!
Neuromodulation by peptides is essential for brain function. By comprehensively mapping neuropeptide signaling in the nematode C. elegans, Ripoll-Sánchez et al. define a dense wireless network whose organization differs in important ways from wired brain circuits. This network is a prototype for understanding neuropeptide signaling networks in larger brains.