Canadian scientists have established for the first time a new mechanism and role for LDL in the development of type 2 diabetes, beyond its traditional role in the development of cardiovascular disease in humans.
Announced today for World Diabetes Day, the work was carried out by Université de Montréal professor May Faraj, director of the nutrition, lipoproteins and cardiometabolic diseases research unit at the Montreal Clinical Research Institute.
Her study, titled “Native low-density lipoproteins are priming signals of the NLRP3 inflammasome/interleukin1β pathway in human adipose tissue and macrophages,” is published in Scientific Reports.
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