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Sep 29, 2023

Older mouse brains rejuvenated by protein found in young blood

Posted by in categories: biotech/medical, genetics, life extension, neuroscience

A protein involved in wound healing can improve learning and memory in ageing mice1.

Platelet factor 4 (PF4) has long been known for its role in promoting blood clotting and sealing broken blood vessels. Now, researchers are wondering whether this signalling molecule could be used to treat age-related cognitive disorders such as Alzheimer’s disease.

“The therapeutic possibilities are very exciting,” says geneticist and anti-ageing scientist David Sinclair at Harvard University in Boston, Massachusetts, who was not involved in the research. The study was published on 16 August in Nature.

Young blood, old brains.


A platelet factor joins the list of blood components that might have anti-ageing effects.

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