An international team of researchers led by the Netherlands Cancer Institute developed a method to better predict the outgrowth of ductal carcinoma in situ (DCIS), a possible precursor of breast cancer, into invasive breast cancer. Using mice into which cells from women with DCIS were inserted, researchers can better identify which DCIS patients are at risk for breast cancer.
The study was published in Cancer Cell and is part of PRECISION, a major international research project on DCIS.
DCIS consists of aberrant cells in the milk ducts of the breast. In the Netherlands, it is found in about 2,300 women a year, about 80% of them detected at breast cancer screening. This is because calcium splashes can be seen on the X-ray of the breast (the mammogram), which may indicate DCIS.
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