MIT neuroscientists have published a key new insight on how working memory functions, in a study published in PLOS Computational Biology.
The researchers at The Picower Institute for Learning and Memory compared measurements of brain cell activity in an animal performing a working memory task with the output of various computer models representing two theories on the underlying mechanism for holding information in mind.
The results favored the newer theory that a network of neurons stores information by making short-lived changes in the connections, or synapses, between them, rather than the traditional theory that memory is maintained by neurons remaining persistently active.
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