Haven’t heard from Fossel in awhile. This is long but well indexed in the notes.
My mission is to drastically improve your life by helping you break bad habits, build and keep new healthy habits to make you the best version of yourself.
This video me, Brent Nally, interviewing Dr. Michael Fossel about Telocyte and telomerase gene therapy on November 16, 2019.
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SHOW NOTES:
0:20 Dr. Michael Fossel intro — Follow Michael on LinkedIn: https://www.linkedin.com/in/michael-fossel-4196255/ ; http://www.michaelfossel.com/
2:00 Planned January 2020 interview with Michael.
2:25 Buy Michael’s 3 books: 1) Reversing Human Aging 2) Cells Aging & Human Disease 3) The Telomerase Revolution.
4:15 https://telocyte.com/
5:07 Aging complexities
8:20 Small molecules won’t reverse human aging.
9:01 People are fixed in their incorrect beliefs about aging.
12:50 Sometimes we have to first go backwards to move forwards. My March 26, 2019 interview with Dr. Ed Park at Recharge Biomedical: https://youtube.com/watch?v=xHgfYKsH0uw&list=UUCwpkla04tVxHJUds2J2aqA
15:55 Economics of radically increasing the human healthspan.
19:01 Leonard Hayflick
21:05 The rate of telomere loss is linked to many organism’s lifespan.
22:30 Lengthening human telomeres in aging cells “resets” the cells to make them biologically younger.
24:10 Cells, Aging, and Human Disease preface.
28:20 human population if we radically increase human healthspan/lifespan.
31:20 biological vs chronological aging
32:25 telomerase activation is the best point of clinical and financial intervention to cure and prevent age related diseases.
37:30 Data generally doesn’t support the idea that making telomerase more active in humans can cause cancer. Michael beliefs this idea has been propagated by misinterpreting data.
45:02 Causation & Pathology in Alzheimer’s Disease.
46:30 standard cell aging process
49:53 What can you do to help cure human aging? understand the concepts, share this info & invest.
53:40 the FDA is excited about Telocyte’s model.
55:30 Phase 1 human FDA trial costs about $10 million but costs should drop after that.
57:50 It costs Telocyte about $4 million to initially produce the telomerase gene therapy they need to treat their first 12 patients.
58:55 Lets “elephant hunt” to find billionaire investors for Telocyte.
1:01:18 Michael discusses BioViva/Integrated Health Systems & Liz Parrish. My July 10, 2019 interview with BioViva CEO Liz Parrish: https://youtube.com/watch?v=oBFTwGPaPr4
1:02:10 My May 30, 2019 interview with Sierra Sciences CEO Dr. Bill Andrews: https://youtube.com/watch?v=Tx9yG6iTROQ
1:09:45 ethics and risks of telomerase gene therapy.
1:11:15 Unnatural selection on Netflix
1:14:30 Is reality a simulation?
1:18:10 The mind is like a parachute. It only works if it’s open. Data trumps everything always.
1:19:50 telomerase activator pills
1:24:30 Dr. Greg Fahy
1:28:40 https://lifelength.com/ & https://teloyears.com/home/
1:32:40 My July 17, 2019 interview with Dr. Aubrey de Grey https://www.youtube.com/watch?v=TquJyz7tGfk
1:38:34 Dr. Michael West
1:41:10 Inject snake venom for anti-aging? https://www.youtube.com/watch?v=8q_m-rDUNw0
1:45:15 Bill Haast https://en.wikipedia.org/wiki/Bill_Haast
1:45:50 My October 6, 2019 interview of Dr. Duncan Ross about Kimera exosomes: https://www.youtube.com/watch?v=X8eIxo3eqvQ&t=3s
1:46:15 Brent’s stem cell’s treatment and recovery playlist https://www.youtube.com/playlist?list=PLGjySL94COVQzsAauqp6lZHHzmzBQSmhH
1:51:52 Dr. Maria Blasco
1:52:45 Michael almost got $1 billion for a non-profit translational research for telomerase gene therapy from a wealthy couple in California in 1999.
1:55:45 Dr. Elizabeth Blackburn
1:57:57 Dr. Elissa Epel
2:00:09 Dr. Calvin Harley
2:02:20 Radical honesty and compassion
2:06:25 I recommend the book: Sapiens by Dr. Yuval Noah Harari
2:11:15 Michael’s fascinating experiences.
2:26:30 telomerase gene therapy economies of scale.
2:35:10 Dr. Peter Attia
2:36:50 Peter Rayson, CEO Telocyte. Curing human aging is a systems approach.
2:39:43 Forever Labs 1 year free cryogenic storage discount code ($250 value): BN801 https://foreverlabs.com
2:42:10 Dave Asprey — lack of funding for Telocyte is holding back the potential cure for Alzheimer’s.
2:44:30 Chan Zuckerberg Initiative
2:49:08 health advice
2:56:38 Viome for microbiome
3:01:04 the best current way to measure someone’s age is guessing based off how they look and behave.
3:04:51 transhumanism and ignosticism
3:08:23 Stay curious to continue learning.
3:16:28 “What important truth do very few people agree with you on?”
3:23:30 be considerate
- Intro music by: SoundSage
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