Important — “The researchers found that sedentary behavior is a significant predictor of thinning of the MTL and that physical activity, even at high levels, is insufficient to offset the harmful effects of sitting for extended periods”
— In the study, both (A) Total medial temporal lobe (MTL) and (B) parahippocampal thickness correlated inversely with hours of sitting/day, controlling for age. Reference: Siddarth P et al (2018), Sedentary behavior associated with reduced medial temporal lobe thickness in middle-aged and older adults. PLOS ONE.
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