They discovered that changes in the bone marrow needed for the cancer to grow have already taken hold in the preceding condition, raising the possibility that early medical intervention could prevent this incurable type of cancer from taking root.
The research, which was funded by the blood cancer charity Bloodwise, is published in the journal Leukemia.
Myeloma affects the plasma cells, a type of white blood cell that originates in the bone marrow. Diagnosed in over 4,000 people a year in the UK, fewer than half of patients survive for longer than five years after diagnosis. Symptoms often include debilitating and painful bone damage, anemia and nausea.
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