Lens regeneration in monkeys after minimally invasive surgery. Slit-lamp microscopy showed regenerating lens tissue grew from the peripheral to the central lens in a circular symmetrical pattern 2–3 months after surgery, reaching the center at 5 months post-surgery; direct illumination showed that the visual axis remained translucent. (credit: Haotian Lin et al./Nature)
Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute, with colleagues in China, have developed an eye lens restoration treatment that has been tested in monkeys and in a small human clinical trial. It produced much fewer surgical complications than the current standard-of-care and resulted in regenerated lenses with superior visual function in all 12 of the pediatric cataract patients who received the new surgery.
Congenital cataracts — lens clouding that occurs at birth or shortly thereafter — is a significant cause of blindness in children.
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