DNA-based lock-and-key pore design allows for precision delivery of drugs to cancer and other cells (credit: Stefan Howorka and Jonathan Burns/UCL)
Scientists at University College London (UCL) and Nanion Technologies in Munich have developed synthetic DNA-based pores that control which molecules can pass through a cell’s wall, achieving more precise drug delivery.
Therapeutics, including anti-cancer drugs, are ferried around the body in nanoscale carriers called vesicles, targeted to different tissues using biological markers. The new DNA-based pore design is intended to improve that process.
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