An anti-aging drug is about to begin human trials.
Category: life extension – Page 655
A Promising Anti-Aging Drug Will Soon Be Tried On Humans
Washington University in St. Louis and Keio University in Japan is set to test the effectiveness and safety of the compound. Starting next month, about 10 healthy people will be administered NMN to see if can improve bodily function and stave off the effects of aging. Should it work, it would become the first bona fide anti-aging intervention available on the market.
A compound called nicotinamide mono nucleotide (NMN) has been shown to slow down the aging process and extend the lifespans of mice. We’re about to find out if it does the same thing to humans.
A planned clinical trial devised by researchers from Washington University in St. Louis and Keio University in Japan is set to test the effectiveness and safety of the compound. Starting next month, about 10 healthy people will be administered NMN to see if can improve bodily function and stave off the effects of aging. Should it work, it would become the first bona fide anti-aging intervention available on the market.
World’s First Longevity SIRT Chocolate
Want to fight aging; eat this new chocolate.
Cambridge UK (PRWEB UK) 19 June 2016 Lycotec Ltd., a biotech company based in Cambridge UK, http://www.lycotec.com announces that they have developed the World’s First Longevity SIRT Chocolate, which after ingestion provides a blood level of unmodified trans-Resveratrol, t-RSV, equal to its level after drinking red wine.
T-RSV is the molecule of plant polyphenol class which is typically present in red grapes, some berries, cocoa and nuts. There are a number of beneficial health effects of t-RSV from cardioprotective to antidiabetic. However, one of its intriguing properties is the ability to activate a group of SIRT genes. These genes are responsible for controlling cellular stress protection and longevity.
When t-RSV is consumed as part of food, or a beverage, or as an isolated extract in the form of most supplements, it quickly gets modified and inactivated in the digestive tract. Drinking red wine is the only known exception when t-RSV can reach the blood in an unmodified active form at a detectable level.
MMTP — Major Mouse Testing Program — Interview with David Gems
Crowdfunding Campaign: https://www.lifespan.io/campaigns/the-major-mouse-testing-program/
We are testing a combination of compounds which clear out dysfunctional cells in the body, called Senolytics, to see if we can extend maximum lifespan and healthspan in mice. Please subscribe, share, and fund our Lifespan.io campaign today!
MMTP — Major Mouse Testing Program.
http://majormouse.org
Is a project by the International Longevity Alliance.
http://longevityalliance.org
Subscribe: https://www.youtube.com/user/LifespanIO
How to Live to 150
I’m 55 years old. I’m shooting for a multihundred-year lifespan. That’s my goal. If you don’t shoot for it, you’re not going to hit it, right?”
I guess he’ll want to speak to George Church.
The author of this titles it “to 150” yet Peter here says multi hundred, and included a pic of Venter who has said he doesn’t think people should live past 120.
Peter Diamandis is leading the charge to crack our genetic code in search of a brighter (much longer) future.
SynBio Advances on Multiple Fronts
List of the who’s who are leading some of key bio programs around nextgen bio/ living cell technologies.
According to GEN’s experts, synthetic biology isn’t yet plug-and-play, but cellular processes are being engineered into biosensing systems as well as biologics production. Soon, for tasks from theranostics to regenerative medicine, “there will be a synbio app for that.”
Zoltan Istvan 2016: Let’s make Americans immortal
USA Today story:
As co-writer for USA TODAY’S “For the Record,” I’ve been writing about the campaigns of Republican, Democratic, Libertarian and Green presidential candidates since the newsletter’s launch last summer. But the first presidential candidate to reach out to me was Zoltan Istvan, the Mill Valley, California-based Transhumanist Party candidate who foresees the merger of humans and technology in the very near future. I spoke by phone with Istvan last week.
Big promises are the hallmark of presidential campaigns.
Four years ago, Newt Gingrich said he’d make the moon the 51st state by 2020. Bernie Sanders has proposed free college education for every American. Donald Trump has promised to build a 1,900-mile wall on the border with Mexico.
Transhumanist Party candidate Zoltan Istvan wants to conquer death.
First phase 1 human aging reversal trials (GDF, Myostatin) in a year or two and George Church discusses how to affordably rejuvenate the whole body
The new goal is to reverse aging, not only in animals, but in humans. And age reversal is essential, as significant age-related disruption has already occurred in most people due to changes in our gene expression profiles.
Gene expression patterns change with age. This influences the rate at which an individual ages, and also determines what senile disorders they are likely to contract. But innovative gene-editing methods based on a unique technology called CRISPR (clustered regularly interspaced short palindromic repeats) are now being successfully harnessed for use as an age-reversal therapy for humans.
In response to these breakthroughs, Life Extension® magazine sent biogerontologist Dr. Gregory M. Fahy to Harvard University to interview Dr. George Church, who is a leading developer of cutting-edge CRISPR techniques. Here, Dr. Church explains remarkable opportunities for transforming human aging that may begin to unfold sooner than most have imagined.